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629 results

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Page 1
Metabolic control of adaptive β-cell proliferation by the protein deacetylase SIRT2.
Wortham M, Ramms B, Zeng C, Benthuysen JR, Sai S, Pollow DP, Liu F, Schlichting M, Harrington AR, Liu B, Prakash TP, Pirie EC, Zhu H, Baghdasarian S, Auwerx J, Shirihai OS, Sander M. Wortham M, et al. Among authors: auwerx j. bioRxiv [Preprint]. 2024 Feb 28:2024.02.24.581864. doi: 10.1101/2024.02.24.581864. bioRxiv. 2024. PMID: 38464227 Free PMC article. Preprint.
High-content phenotypic analysis of a C. elegans recombinant inbred population identifies genetic and molecular regulators of lifespan.
Gao AW, Alam GE, Zhu Y, Li W, Katsyuba E, Sulc J, Li TY, Li X, Overmyer KA, Lalou A, Mouchiroud L, Sleiman MB, Cornaglia M, Morel JD, Houtkooper RH, Coon JJ, Auwerx J. Gao AW, et al. Among authors: auwerx j. bioRxiv [Preprint]. 2024 Jan 16:2024.01.15.575638. doi: 10.1101/2024.01.15.575638. bioRxiv. 2024. PMID: 38293129 Free PMC article. Preprint.
Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction.
Wohlwend M, Laurila PP, Goeminne LJE, Lima T, Daskalaki I, Li X, von Alvensleben G, Crisol B, Mangione R, Gallart-Ayala H, Lalou A, Burri O, Butler S, Morris J, Turner N, Ivanisevic J, Auwerx J. Wohlwend M, et al. Among authors: auwerx j. Elife. 2024 Mar 20;12:RP90522. doi: 10.7554/eLife.90522. Elife. 2024. PMID: 38506902 Free PMC article.
Cyclo His-Pro Attenuates Muscle Degeneration in Murine Myopathy Models.
De Masi A, Zanou N, Strotjohann K, Lee D, Lima TI, Li X, Jeon J, Place N, Jung HY, Auwerx J. De Masi A, et al. Among authors: auwerx j. Adv Sci (Weinh). 2024 May 10:e2305927. doi: 10.1002/advs.202305927. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 38728626
Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling.
Beirowski B, Gustin J, Armour SM, Yamamoto H, Viader A, North BJ, Michán S, Baloh RH, Golden JP, Schmidt RE, Sinclair DA, Auwerx J, Milbrandt J. Beirowski B, et al. Among authors: auwerx j. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):E952-61. doi: 10.1073/pnas.1104969108. Epub 2011 Sep 26. Proc Natl Acad Sci U S A. 2011. PMID: 21949390 Free PMC article.
KAT2B Is Required for Pancreatic Beta Cell Adaptation to Metabolic Stress by Controlling the Unfolded Protein Response.
Rabhi N, Denechaud PD, Gromada X, Hannou SA, Zhang H, Rashid T, Salas E, Durand E, Sand O, Bonnefond A, Yengo L, Chavey C, Bonner C, Kerr-Conte J, Abderrahmani A, Auwerx J, Fajas L, Froguel P, Annicotte JS. Rabhi N, et al. Among authors: auwerx j. Cell Rep. 2016 May 3;15(5):1051-1061. doi: 10.1016/j.celrep.2016.03.079. Epub 2016 Apr 21. Cell Rep. 2016. PMID: 27117420 Free article.
The role of sirtuins in the control of metabolic homeostasis.
Yu J, Auwerx J. Yu J, et al. Among authors: auwerx j. Ann N Y Acad Sci. 2009 Sep;1173 Suppl 1(0 1):E10-9. doi: 10.1111/j.1749-6632.2009.04952.x. Ann N Y Acad Sci. 2009. PMID: 19751409 Free PMC article. Review.
Hippo-YAP/TAZ signalling coordinates adipose plasticity and energy balance by uncoupling leptin expression from fat mass.
Choi S, Kang JG, Tran YTH, Jeong SH, Park KY, Shin H, Kim YH, Park M, Nahmgoong H, Seol T, Jeon H, Kim Y, Park S, Kim HJ, Kim MS, Li X, Bou Sleiman M, Lee E, Choi J, Eisenbarth D, Lee SH, Cho S, Moore DD, Auwerx J, Kim IY, Kim JB, Park JE, Lim DS, Suh JM. Choi S, et al. Among authors: auwerx j. Nat Metab. 2024 May;6(5):847-860. doi: 10.1038/s42255-024-01045-4. Epub 2024 May 29. Nat Metab. 2024. PMID: 38811804
Skeletal Muscle SIRT3 Deficiency Contributes to Pulmonary Vascular Remodeling in Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction.
Jheng JR, Bai Y, Noda K, Huot JR, Cook T, Fisher A, Chen YY, Goncharov DA, Goncharova EA, Simon MA, Zhang Y, Forman DE, Rojas M, Machado RF, Auwerx J, Gladwin MT, Lai YC. Jheng JR, et al. Among authors: auwerx j. Circulation. 2024 May 28. doi: 10.1161/CIRCULATIONAHA.124.068624. Online ahead of print. Circulation. 2024. PMID: 38804138
629 results