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Metabolic control of adaptive β-cell proliferation by the protein deacetylase SIRT2.
Wortham M, Ramms B, Zeng C, Benthuysen JR, Sai S, Pollow DP, Liu F, Schlichting M, Harrington AR, Liu B, Prakash TP, Pirie EC, Zhu H, Baghdasarian S, Auwerx J, Shirihai OS, Sander M. Wortham M, et al. bioRxiv [Preprint]. 2024 Feb 28:2024.02.24.581864. doi: 10.1101/2024.02.24.581864. bioRxiv. 2024. PMID: 38464227 Free PMC article. Preprint.
A vascularized 3D model of the human pancreatic islet forex vivostudy of immune cell-islet interaction.
Bender RHF, O'Donnell BT, Shergill B, Pham BQ, Tahmouresie S, Sanchez CN, Juat DJ, Hatch MMS, Shirure VS, Wortham M, Nguyen-Ngoc KV, Jun Y, Gaetani R, Christman KL, Teyton L, George SC, Sander M, Hughes CCW. Bender RHF, et al. Among authors: wortham m. Biofabrication. 2024 Jan 11;16(2):025001. doi: 10.1088/1758-5090/ad17d0. Biofabrication. 2024. PMID: 38128127 Free PMC article.
Nutrient regulation of the islet epigenome controls adaptive insulin secretion.
Wortham M, Liu F, Harrington AR, Fleischman JY, Wallace M, Mulas F, Mallick M, Vinckier NK, Cross BR, Chiou J, Patel NA, Sui Y, McGrail C, Jun Y, Wang G, Jhala US, Schüle R, Shirihai OS, Huising MO, Gaulton KJ, Metallo CM, Sander M. Wortham M, et al. J Clin Invest. 2023 Apr 17;133(8):e165208. doi: 10.1172/JCI165208. J Clin Invest. 2023. PMID: 36821378 Free PMC article.
Sizing up beta cells made from stem cells.
Nguyen-Ngoc KV, Wortham M, Sander M. Nguyen-Ngoc KV, et al. Among authors: wortham m. Nat Biotechnol. 2022 Jul;40(7):1006-1008. doi: 10.1038/s41587-022-01271-9. Nat Biotechnol. 2022. PMID: 35288669 No abstract available.
Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance.
Shum M, Segawa M, Gharakhanian R, Viñuela A, Wortham M, Baghdasarian S, Wolf DM, Sereda SB, Nocito L, Stiles L, Zhou Z, Gutierrez V, Sander M, Shirihai OS, Liesa M. Shum M, et al. Among authors: wortham m. Mol Metab. 2022 Jan;55:101403. doi: 10.1016/j.molmet.2021.101403. Epub 2021 Nov 23. Mol Metab. 2022. PMID: 34823065 Free PMC article.
23 results