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RAC1 as a Therapeutic Target in Malignant Melanoma.
Cannon AC, Uribe-Alvarez C, Chernoff J. Cannon AC, et al. Among authors: chernoff j. Trends Cancer. 2020 Jun;6(6):478-488. doi: 10.1016/j.trecan.2020.02.021. Epub 2020 Mar 18. Trends Cancer. 2020. PMID: 32460002 Free PMC article. Review.
Resistance to BET Bromodomain Inhibitors Is Mediated by Kinome Reprogramming in Ovarian Cancer.
Kurimchak AM, Shelton C, Duncan KE, Johnson KJ, Brown J, O'Brien S, Gabbasov R, Fink LS, Li Y, Lounsbury N, Abou-Gharbia M, Childers WE, Connolly DC, Chernoff J, Peterson JR, Duncan JS. Kurimchak AM, et al. Among authors: chernoff j. Cell Rep. 2016 Aug 2;16(5):1273-1286. doi: 10.1016/j.celrep.2016.06.091. Epub 2016 Jul 21. Cell Rep. 2016. PMID: 27452461 Free PMC article.
Functional proteomics interrogation of the kinome identifies MRCKA as a therapeutic target in high-grade serous ovarian carcinoma.
Kurimchak AM, Herrera-Montávez C, Brown J, Johnson KJ, Sodi V, Srivastava N, Kumar V, Deihimi S, O'Brien S, Peri S, Mantia-Smaldone GM, Jain A, Winters RM, Cai KQ, Chernoff J, Connolly DC, Duncan JS. Kurimchak AM, et al. Among authors: chernoff j. Sci Signal. 2020 Feb 18;13(619):eaax8238. doi: 10.1126/scisignal.aax8238. Sci Signal. 2020. PMID: 32071169 Free PMC article.
Targeting effector pathways in RAC1P29S-driven malignant melanoma.
Uribe-Alvarez C, Guerrero-Rodríguez SL, Rhodes J, Cannon A, Chernoff J, Araiza-Olivera D. Uribe-Alvarez C, et al. Among authors: chernoff j. Small GTPases. 2021 Jul;12(4):273-281. doi: 10.1080/21541248.2020.1728469. Epub 2020 Feb 17. Small GTPases. 2021. PMID: 32043900 Free PMC article.
Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling.
Sementino E, Kadariya Y, Cheung M, Menges CW, Tan Y, Kukuyan AM, Shrestha U, Karchugina S, Cai KQ, Peri S, Duncan JS, Chernoff J, Testa JR. Sementino E, et al. Among authors: chernoff j. Mol Cancer Res. 2022 May 4;20(5):699-711. doi: 10.1158/1541-7786.MCR-21-0837. Mol Cancer Res. 2022. PMID: 35082167 Free PMC article.
224 results