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Designed mosaic nanoparticles enhance cross-reactive immune responses in mice.
Wang E, Cohen AA, Caldera LF, Keeffe JR, Rorick AV, Aida YM, Gnanapragasam PNP, Bjorkman PJ, Chakraborty AK. Wang E, et al. Among authors: keeffe jr. bioRxiv [Preprint]. 2024 Feb 28:2024.02.28.582544. doi: 10.1101/2024.02.28.582544. bioRxiv. 2024. PMID: 38464322 Free PMC article. Preprint.
Designed oligomers of cyanovirin-N show enhanced HIV neutralization.
Keeffe JR, Gnanapragasam PN, Gillespie SK, Yong J, Bjorkman PJ, Mayo SL. Keeffe JR, et al. Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14079-84. doi: 10.1073/pnas.1108777108. Epub 2011 Jul 28. Proc Natl Acad Sci U S A. 2011. PMID: 21799112 Free PMC article.
Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Escolano A, Gristick HB, Abernathy ME, Merkenschlager J, Gautam R, Oliveira TY, Pai J, West AP Jr, Barnes CO, Cohen AA, Wang H, Golijanin J, Yost D, Keeffe JR, Wang Z, Zhao P, Yao KH, Bauer J, Nogueira L, Gao H, Voll AV, Montefiori DC, Seaman MS, Gazumyan A, Silva M, McGuire AT, Stamatatos L, Irvine DJ, Wells L, Martin MA, Bjorkman PJ, Nussenzweig MC. Escolano A, et al. Among authors: keeffe jr. Nature. 2019 Jun;570(7762):468-473. doi: 10.1038/s41586-019-1250-z. Epub 2019 May 29. Nature. 2019. PMID: 31142836 Free PMC article.
Detection and characterization of the SARS-CoV-2 lineage B.1.526 in New York.
West AP Jr, Wertheim JO, Wang JC, Vasylyeva TI, Havens JL, Chowdhury MA, Gonzalez E, Fang CE, Di Lonardo SS, Hughes S, Rakeman JL, Lee HH, Barnes CO, Gnanapragasam PNP, Yang Z, Gaebler C, Caskey M, Nussenzweig MC, Keeffe JR, Bjorkman PJ. West AP Jr, et al. Among authors: keeffe jr. bioRxiv [Preprint]. 2021 Apr 22:2021.02.14.431043. doi: 10.1101/2021.02.14.431043. bioRxiv. 2021. PMID: 33907745 Free PMC article. Updated. Preprint.
Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies.
Jette CA, Cohen AA, Gnanapragasam PNP, Muecksch F, Lee YE, Huey-Tubman KE, Schmidt F, Hatziioannou T, Bieniasz PD, Nussenzweig MC, West AP Jr, Keeffe JR, Bjorkman PJ, Barnes CO. Jette CA, et al. Among authors: keeffe jr. bioRxiv [Preprint]. 2021 Apr 26:2021.04.23.441195. doi: 10.1101/2021.04.23.441195. bioRxiv. 2021. PMID: 33948592 Free PMC article. Updated. Preprint.
B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV.
Scheid JF, Barnes CO, Eraslan B, Hudak A, Keeffe JR, Cosimi LA, Brown EM, Muecksch F, Weisblum Y, Zhang S, Delorey T, Woolley AE, Ghantous F, Park SM, Phillips D, Tusi B, Huey-Tubman KE, Cohen AA, Gnanapragasam PNP, Rzasa K, Hatziioanno T, Durney MA, Gu X, Tada T, Landau NR, West AP Jr, Rozenblatt-Rosen O, Seaman MS, Baden LR, Graham DB, Deguine J, Bieniasz PD, Regev A, Hung D, Bjorkman PJ, Xavier RJ. Scheid JF, et al. Among authors: keeffe jr. Cell. 2021 Jun 10;184(12):3205-3221.e24. doi: 10.1016/j.cell.2021.04.032. Epub 2021 Apr 24. Cell. 2021. PMID: 34015271 Free PMC article.
Detection and characterization of the SARS-CoV-2 lineage B.1.526 in New York.
West AP Jr, Wertheim JO, Wang JC, Vasylyeva TI, Havens JL, Chowdhury MA, Gonzalez E, Fang CE, Di Lonardo SS, Hughes S, Rakeman JL, Lee HH, Barnes CO, Gnanapragasam PNP, Yang Z, Gaebler C, Caskey M, Nussenzweig MC, Keeffe JR, Bjorkman PJ. West AP Jr, et al. Among authors: keeffe jr. Nat Commun. 2021 Aug 9;12(1):4886. doi: 10.1038/s41467-021-25168-4. Nat Commun. 2021. PMID: 34373458 Free PMC article.
50 results