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Page 1
Shared and Distinct Genomics of Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Embolism.
Liley J, Newnham M, Bleda M, Bunclark K, Auger W, Barbera JA, Bogaard H, Delcroix M, Fernandes TM, Howard L, Jenkins D, Lang I, Mayer E, Rhodes C, Simpson M, Southgate L, Trembath R, Wharton J, Wilkins MR, Gräf S, Morrell N, Pepke Zaba J, Toshner M. Liley J, et al. Among authors: wilkins mr. Am J Respir Crit Care Med. 2024 Mar 12. doi: 10.1164/rccm.202307-1236OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 38470220
Whole-Blood RNA Profiles Associated with Pulmonary Arterial Hypertension and Clinical Outcome.
Rhodes CJ, Otero-Núñez P, Wharton J, Swietlik EM, Kariotis S, Harbaum L, Dunning MJ, Elinoff JM, Errington N, Thompson AAR, Iremonger J, Coghlan JG, Corris PA, Howard LS, Kiely DG, Church C, Pepke-Zaba J, Toshner M, Wort SJ, Desai AA, Humbert M, Nichols WC, Southgate L, Trégouët DA, Trembath RC, Prokopenko I, Gräf S, Morrell NW, Wang D, Lawrie A, Wilkins MR. Rhodes CJ, et al. Among authors: wilkins mr. Am J Respir Crit Care Med. 2020 Aug 15;202(4):586-594. doi: 10.1164/rccm.202003-0510OC. Am J Respir Crit Care Med. 2020. PMID: 32352834 Free PMC article.
Using the Plasma Proteome for Risk Stratifying Patients with Pulmonary Arterial Hypertension.
Rhodes CJ, Wharton J, Swietlik EM, Harbaum L, Girerd B, Coghlan JG, Lordan J, Church C, Pepke-Zaba J, Toshner M, Wort SJ, Kiely DG, Condliffe R, Lawrie A, Gräf S, Montani D, Boucly A, Sitbon O, Humbert M, Howard LS, Morrell NW, Wilkins MR. Rhodes CJ, et al. Among authors: wilkins mr. Am J Respir Crit Care Med. 2022 May 1;205(9):1102-1111. doi: 10.1164/rccm.202105-1118OC. Am J Respir Crit Care Med. 2022. PMID: 35081018 Free PMC article.
Plasma metabolomics exhibit response to therapy in chronic thromboembolic pulmonary hypertension.
Swietlik EM, Ghataorhe P, Zalewska KI, Wharton J, Howard LS, Taboada D, Cannon JE; UK National Cohort Study of PAH; Morrell NW, Wilkins MR, Toshner M, Pepke-Zaba J, Rhodes CJ. Swietlik EM, et al. Among authors: wilkins mr. Eur Respir J. 2021 Apr 1;57(4):2003201. doi: 10.1183/13993003.03201-2020. Print 2021 Apr. Eur Respir J. 2021. PMID: 33060150 Free PMC article.
Mendelian randomisation and experimental medicine approaches to interleukin-6 as a drug target in pulmonary arterial hypertension.
Toshner M, Church C, Harbaum L, Rhodes C, Villar Moreschi SS, Liley J, Jones R, Arora A, Batai K, Desai AA, Coghlan JG, Gibbs JSR, Gor D, Gräf S, Harlow L, Hernandez-Sanchez J, Howard LS, Humbert M, Karnes J, Kiely DG, Kittles R, Knightbridge E, Lam B, Lutz KA, Nichols WC, Pauciulo MW, Pepke-Zaba J, Suntharalingam J, Soubrier F, Trembath RC, Schwantes-An TL, Wort SJ, Wilkins MR, Gaine S, Morrell NW, Corris PA; Uniphy Clinical Trials Network. Toshner M, et al. Among authors: wilkins mr. Eur Respir J. 2022 Mar 10;59(3):2002463. doi: 10.1183/13993003.02463-2020. Print 2022 Mar. Eur Respir J. 2022. PMID: 34588193 Free PMC article.
Autoimmunity Is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension.
Jones RJ, De Bie EMDD, Groves E, Zalewska KI, Swietlik EM, Treacy CM, Martin JM, Polwarth G, Li W, Guo J, Baxendale HE, Coleman S, Savinykh N, Coghlan JG, Corris PA, Howard LS, Johnson MK, Church C, Kiely DG, Lawrie A, Lordan JL, Mackenzie Ross RV, Pepke Zaba J, Wilkins MR, Wort SJ, Fiorillo E, Orrù V, Cucca F, Rhodes CJ, Gräf S, Morrell NW, McKinney EF, Wallace C, Toshner M; UK National Cohort Study of Idiopathic and Heritable PAH Consortium. Jones RJ, et al. Among authors: wilkins mr. Am J Respir Crit Care Med. 2022 Jul 1;206(1):81-93. doi: 10.1164/rccm.202108-1919OC. Am J Respir Crit Care Med. 2022. PMID: 35316153 Free PMC article.
Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension.
Harbaum L, Rhodes CJ, Wharton J, Lawrie A, Karnes JH, Desai AA, Nichols WC, Humbert M, Montani D, Girerd B, Sitbon O, Boehm M, Novoyatleva T, Schermuly RT, Ghofrani HA, Toshner M, Kiely DG, Howard LS, Swietlik EM, Gräf S, Pietzner M, Morrell NW, Wilkins MR; U.K. National Institute for Health Research BioResource Rare Diseases Consortium, U.K. Pulmonary Arterial Hypertension Cohort Study Consortium, and U.S. Pulmonary Arterial Hypertension Biobank Consortium. Harbaum L, et al. Among authors: wilkins mr. Am J Respir Crit Care Med. 2022 Jun 15;205(12):1449-1460. doi: 10.1164/rccm.202109-2106OC. Am J Respir Crit Care Med. 2022. PMID: 35394406 Free PMC article.
Genetic and molecular mechanisms of pulmonary hypertension.
Morrell NW, Wilkins MR. Morrell NW, et al. Among authors: wilkins mr. Clin Med (Lond). 2001 Mar-Apr;1(2):138-45. doi: 10.7861/clinmedicine.1-2-138. Clin Med (Lond). 2001. PMID: 11333460 Free PMC article. Review.
Deprivation and prognosis in patients with pulmonary arterial hypertension: missing the effect of deprivation on a rare disease?
Sofianopoulou E, Church C, Coghlan G, Howard L, Johnson M, Kiely DG, Lawrie A, Lordan J, Wilkins MR, Wort SJ, Morrell NW, Toshner MR. Sofianopoulou E, et al. Among authors: wilkins mr. Eur Respir J. 2020 Aug 13;56(2):1902334. doi: 10.1183/13993003.02334-2019. Print 2020 Aug. Eur Respir J. 2020. PMID: 32299862 Free PMC article.
568 results