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The prostaglandin E2 EP3 receptor has disparate effects on islet insulin secretion and content in β-cells in a high-fat diet-induced mouse model of obesity.
Neuman JC, Reuter A, Carbajal KA, Schaid MD, Kelly G, Connors K, Kaiser C, Krause J, Hurley LD, Olvera A, Davis DB, Wisinski JA, Gannon M, Kimple ME. Neuman JC, et al. Among authors: davis db. Am J Physiol Endocrinol Metab. 2024 May 1;326(5):E567-E576. doi: 10.1152/ajpendo.00061.2023. Epub 2024 Mar 13. Am J Physiol Endocrinol Metab. 2024. PMID: 38477664
Systemic Metabolic Alterations Correlate with Islet-Level Prostaglandin E2 Production and Signaling Mechanisms That Predict β-Cell Dysfunction in a Mouse Model of Type 2 Diabetes.
Schaid MD, Zhu Y, Richardson NE, Patibandla C, Ong IM, Fenske RJ, Neuman JC, Guthery E, Reuter A, Sandhu HK, Fuller MH, Cox ED, Davis DB, Layden BT, Brasier AR, Lamming DW, Ge Y, Kimple ME. Schaid MD, et al. Among authors: davis db. Metabolites. 2021 Jan 16;11(1):58. doi: 10.3390/metabo11010058. Metabolites. 2021. PMID: 33467110 Free PMC article.
Human Islet Expression Levels of Prostaglandin E2 Synthetic Enzymes, But Not Prostaglandin EP3 Receptor, Are Positively Correlated with Markers of β-Cell Function and Mass in Nondiabetic Obesity.
Truchan NA, Fenske RJ, Sandhu HK, Weeks AM, Patibandla C, Wancewicz B, Pabich S, Reuter A, Harrington JM, Brill AL, Peter DC, Nall R, Daniels M, Punt M, Kaiser CE, Cox ED, Ge Y, Davis DB, Kimple ME. Truchan NA, et al. Among authors: davis db. ACS Pharmacol Transl Sci. 2021 Jun 16;4(4):1338-1348. doi: 10.1021/acsptsci.1c00045. eCollection 2021 Aug 13. ACS Pharmacol Transl Sci. 2021. PMID: 34423270 Free PMC article.
Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line.
Krautkramer KA, Linnemann AK, Fontaine DA, Whillock AL, Harris TW, Schleis GJ, Truchan NA, Marty-Santos L, Lavine JA, Cleaver O, Kimple ME, Davis DB. Krautkramer KA, et al. Among authors: davis db. Am J Physiol Endocrinol Metab. 2013 Sep 1;305(5):E600-10. doi: 10.1152/ajpendo.00147.2013. Epub 2013 Jul 16. Am J Physiol Endocrinol Metab. 2013. PMID: 23860123 Free PMC article.
The gastrin-releasing peptide analog bombesin preserves exocrine and endocrine pancreas morphology and function during parenteral nutrition.
Pierre JF, Neuman JC, Brill AL, Brar HK, Thompson MF, Cadena MT, Connors KM, Busch RA, Heneghan AF, Cham CM, Jones EK, Kibbe CR, Davis DB, Groblewski GE, Kudsk KA, Kimple ME. Pierre JF, et al. Among authors: davis db. Am J Physiol Gastrointest Liver Physiol. 2015 Sep 15;309(6):G431-42. doi: 10.1152/ajpgi.00072.2015. Epub 2015 Jul 16. Am J Physiol Gastrointest Liver Physiol. 2015. PMID: 26185331 Free PMC article.
96 results