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Discovery of the Clinical Candidate IDOR-1117-2520: A Potent and Selective Antagonist of CCR6 for Autoimmune Diseases.
Meyer EA, Croxford AL, Gnerre C, Kulig P, Murphy MJ, Jacob EM, Schäfer G, Richard-Bildstein S, Aissaoui H, Bouis P, Ertel EA, de Kanter R, Keller MP, Lüthi U, Caroff E. Meyer EA, et al. Among authors: murphy mj. J Med Chem. 2024 May 23;67(10):8077-8098. doi: 10.1021/acs.jmedchem.4c00186. Epub 2024 May 10. J Med Chem. 2024. PMID: 38727100
(-)-6-Chloro-2-[(1-furo[2, 3-c]pyridin-5-ylethyl)thio]-4-pyrimidinamine, PNU-142721, a new broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitor.
Wishka DG, Graber DR, Kopta LA, Olmsted RA, Friis JM, Hosley JD, Adams WJ, Seest EP, Castle TM, Dolak LA, Keiser BJ, Yagi Y, Jeganathan A, Schlachter ST, Murphy MJ, Cleek GJ, Nugent RA, Poppe SM, Swaney SM, Han F, Watt W, White WL, Poel TJ, Thomas RC, Morris J, et al. Wishka DG, et al. Among authors: murphy mj. J Med Chem. 1998 Apr 23;41(9):1357-60. doi: 10.1021/jm9801049. J Med Chem. 1998. PMID: 9554867 No abstract available.
Paradoxical Psoriasis.
Abdelghaffar M, Kottilil S, Murphy MJ, Cohen JM, Damsky W. Abdelghaffar M, et al. Among authors: murphy mj. Dermatol Clin. 2024 Jul;42(3):471-480. doi: 10.1016/j.det.2024.02.011. Epub 2024 Apr 10. Dermatol Clin. 2024. PMID: 38796276 Review.
617 results