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Discovery and Characterization of a New Class of C5aR1 Antagonists Showing In Vivo Activity.
J Med Chem. 2024 Mar 14;67(5):4100-4119. doi: 10.1021/acs.jmedchem.3c02375. Epub 2024 Mar 4.
J Med Chem. 2024.
PMID: 38482828
The orally active melanocortin-4 receptor antagonist BL-6020/979: a promising candidate for the treatment of cancer cachexia.
Dallmann R, Weyermann P, Anklin C, Boroff M, Bray-French K, Cardel B, Courdier-Fruh I, Deppe H, Dubach-Powell J, Erb M, Haefeli RH, Henneböhle M, Herzner H, Hufschmid M, Marks DL, Nordhoff S, Papp M, Rummey C, Santos G, Schärer F, Siendt H, Soeberdt M, Sumanovski LT, Terinek M, Mondadori C, Güven N, Feurer A.
Dallmann R, et al. Among authors: siendt h.
J Cachexia Sarcopenia Muscle. 2011 Sep;2(3):163-174. doi: 10.1007/s13539-011-0039-1. Epub 2011 Aug 28.
J Cachexia Sarcopenia Muscle. 2011.
PMID: 21966642
Free PMC article.
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Effect of calpain and proteasome inhibition on Ca2+-dependent proteolysis and muscle histopathology in the mdx mouse.
Briguet A, Erb M, Courdier-Fruh I, Barzaghi P, Santos G, Herzner H, Lescop C, Siendt H, Henneboehle M, Weyermann P, Magyar JP, Dubach-Powell J, Metz G, Meier T.
Briguet A, et al. Among authors: siendt h.
FASEB J. 2008 Dec;22(12):4190-200. doi: 10.1096/fj.07-099036. Epub 2008 Aug 26.
FASEB J. 2008.
PMID: 18728218
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Novel cell-penetrating alpha-keto-amide calpain inhibitors as potential treatment for muscular dystrophy.
Lescop C, Herzner H, Siendt H, Bolliger R, Henneböhle M, Weyermann P, Briguet A, Courdier-Fruh I, Erb M, Foster M, Meier T, Magyar JP, von Sprecher A.
Lescop C, et al. Among authors: siendt h.
Bioorg Med Chem Lett. 2005 Dec 1;15(23):5176-81. doi: 10.1016/j.bmcl.2005.08.064. Epub 2005 Sep 26.
Bioorg Med Chem Lett. 2005.
PMID: 16185867
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