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Structural insights reveal interplay between LAG-3 homodimerization, ligand binding, and function.
Silberstein JL, Du J, Chan KW, Frank JA, Mathews II, Kim YB, You J, Lu Q, Liu J, Philips EA, Liu P, Rao E, Fernandez D, Rodriguez GE, Kong XP, Wang J, Cochran JR. Silberstein JL, et al. Among authors: chan kw. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2310866121. doi: 10.1073/pnas.2310866121. Epub 2024 Mar 14. Proc Natl Acad Sci U S A. 2024. PMID: 38483996
HIV-1 interaction with an O-glycan-specific bacterial lectin enhances virus infectivity and resistance to neutralization by antibodies.
Heindel DW, Figueroa Acosta DM, Goff M, Yengo CK, Jan M, Liu X, Wang XH, Petrova MI, Zhang M, Sagar M, Barnette P, Pandey S, Hessell AJ, Chan KW, Kong XP, Chen BK, Mahal LK, Bensing BA, Hioe CE. Heindel DW, et al. Among authors: chan kw. Res Sq [Preprint]. 2024 Jan 3:rs.3.rs-2596269. doi: 10.21203/rs.3.rs-2596269/v1. Res Sq. 2024. PMID: 36824869 Free PMC article. Preprint.
Human CD4-binding site antibody elicited by polyvalent DNA prime-protein boost vaccine neutralizes cross-clade tier-2-HIV strains.
Wang S, Chan KW, Wei D, Ma X, Liu S, Hu G, Park S, Pan R, Gu Y, Nazzari AF, Olia AS, Xu K, Lin BC, Louder MK, McKee K, Doria-Rose NA, Montefiori D, Seaman MS, Zhou T, Kwong PD, Arthos J, Kong XP, Lu S. Wang S, et al. Among authors: chan kw. Nat Commun. 2024 May 21;15(1):4301. doi: 10.1038/s41467-024-48514-8. Nat Commun. 2024. PMID: 38773089 Free PMC article.
VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA.
Jia M, Liberatore RA, Guo Y, Chan KW, Pan R, Lu H, Waltari E, Mittler E, Chandran K, Finzi A, Kaufmann DE, Seaman MS, Ho DD, Shapiro L, Sheng Z, Kong XP, Bieniasz PD, Wu X. Jia M, et al. Among authors: chan kw. Cell Host Microbe. 2020 Jun 10;27(6):963-975.e5. doi: 10.1016/j.chom.2020.03.024. Epub 2020 Apr 20. Cell Host Microbe. 2020. PMID: 32315598 Free PMC article.
Human CD4-Binding Site Antibody Elicited by Polyvalent DNA Prime-Protein Boost Vaccine Neutralizes Cross-Clade Tier-2-HIV Strains.
Wang S, Chan KW, Wei D, Ma X, Liu S, Hu G, Park S, Pan R, Gu Y, Nazzari AF, Olia AS, Xu K, Lin BC, Louder MK, Doria-Rose NA, Montefiori D, Seaman MS, Zhou T, Kwong PD, Arthos J, Kong XP, Lu S. Wang S, et al. Among authors: chan kw. Res Sq [Preprint]. 2023 Oct 20:rs.3.rs-3360161. doi: 10.21203/rs.3.rs-3360161/v1. Res Sq. 2023. PMID: 37886518 Free PMC article. Preprint.
1,213 results