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Modular vector assembly enables rapid assessment of emerging CRISPR technologies.
Cell Genom. 2024 Mar 13;4(3):100519. doi: 10.1016/j.xgen.2024.100519.
Cell Genom. 2024.
PMID: 38484704
Free PMC article.
Optimization of Cas12a for multiplexed genome-scale transcriptional activation.
Griffith AL, Zheng F, McGee AV, Miller NW, Szegletes ZM, Reint G, Gademann F, Nwolah I, Hegde M, Liu YV, Goodale A, Doench JG.
Griffith AL, et al. Among authors: szegletes zm.
Cell Genom. 2023 Sep 1;3(9):100387. doi: 10.1016/j.xgen.2023.100387. eCollection 2023 Sep 13.
Cell Genom. 2023.
PMID: 37719144
Free PMC article.
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Modular vector assembly enables rapid assessment of emerging CRISPR technologies.
McGee AV, Liu YV, Griffith AL, Szegletes ZM, Wen B, Kraus C, Miller NW, Steger RJ, Velasco BE, Bosch JA, Zirin JD, Viswanatha R, Sontheimer EJ, Goodale A, Greene MA, Green TM, Doench JG.
McGee AV, et al. Among authors: szegletes zm.
bioRxiv [Preprint]. 2023 Oct 27:2023.10.25.564061. doi: 10.1101/2023.10.25.564061.
bioRxiv. 2023.
PMID: 37961518
Free PMC article.
Updated.
Preprint.
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Massively parallel assessment of human variants with base editor screens.
Hanna RE, Hegde M, Fagre CR, DeWeirdt PC, Sangree AK, Szegletes Z, Griffith A, Feeley MN, Sanson KR, Baidi Y, Koblan LW, Liu DR, Neal JT, Doench JG.
Hanna RE, et al.
Cell. 2021 Feb 18;184(4):1064-1080.e20. doi: 10.1016/j.cell.2021.01.012.
Cell. 2021.
PMID: 33606977
Free article.
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Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2.
Sangree AK, Griffith AL, Szegletes ZM, Roy P, DeWeirdt PC, Hegde M, McGee AV, Hanna RE, Doench JG.
Sangree AK, et al. Among authors: szegletes zm.
Nat Commun. 2022 Mar 14;13(1):1318. doi: 10.1038/s41467-022-28884-7.
Nat Commun. 2022.
PMID: 35288574
Free PMC article.
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Telomerase inhibition is an effective therapeutic strategy in TERT promoter-mutant glioblastoma models with low tumor volume.
Aquilanti E, Kageler L, Watson J, Baird DM, Jones RE, Hodges M, Szegletes ZM, Doench JG, Strathdee CA, Figueroa JRMF, Ligon KL, Beck M, Wen PY, Meyerson M.
Aquilanti E, et al. Among authors: szegletes zm.
Neuro Oncol. 2023 Jul 6;25(7):1275-1285. doi: 10.1093/neuonc/noad024.
Neuro Oncol. 2023.
PMID: 36694348
Free PMC article.
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