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Pharmacokinetic Effects of Different Models of Nonalcoholic Fatty Liver Disease in Transgenic Humanized OATP1B Mice.
Drug Metab Dispos. 2024 Apr 16;52(5):355-367. doi: 10.1124/dmd.123.001607.
Drug Metab Dispos. 2024.
PMID: 38485280
Free PMC article.
Goldenseal-Mediated Inhibition of Intestinal Uptake Transporters Decreases Metformin Systemic Exposure in Mice.
Oyanna VO, Garcia-Torres KY, Bechtold BJ, Lynch KD, Call MR, Horváth M, Manwill PK, Graf TN, Cech NB, Oberlies NH, Paine MF, Clarke JD.
Oyanna VO, et al. Among authors: bechtold bj.
Drug Metab Dispos. 2023 Nov;51(11):1483-1489. doi: 10.1124/dmd.123.001360. Epub 2023 Aug 10.
Drug Metab Dispos. 2023.
PMID: 37562957
Free PMC article.
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Multi-factorial pharmacokinetic interactions: unraveling complexities in precision drug therapy.
Bechtold B, Clarke J.
Bechtold B, et al.
Expert Opin Drug Metab Toxicol. 2021 Apr;17(4):397-412. doi: 10.1080/17425255.2021.1867105. Epub 2021 Jan 20.
Expert Opin Drug Metab Toxicol. 2021.
PMID: 33339463
Free PMC article.
Review.
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Hepatic organic anion transporting polypeptides mediate disposition of milk thistle flavonolignans and pharmacokinetic silymarin-drug interactions.
Lynch KD, Montonye ML, Tian DD, Arman T, Oyanna VO, Bechtold BJ, Graf TN, Oberlies NH, Paine MF, Clarke JD.
Lynch KD, et al. Among authors: bechtold bj.
Phytother Res. 2021 Jun;35(6):3286-3297. doi: 10.1002/ptr.7049. Epub 2021 Feb 15.
Phytother Res. 2021.
PMID: 33587330
Free PMC article.
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Green Tea Catechins Decrease Solubility of Raloxifene In Vitro and Its Systemic Exposure in Mice.
Oyanna VO, Bechtold BJ, Lynch KD, Ridge Call M, Graf TN, Oberlies NH, Clarke JD.
Oyanna VO, et al. Among authors: bechtold bj.
Pharm Res. 2024 Mar;41(3):557-566. doi: 10.1007/s11095-024-03662-w. Epub 2024 Feb 1.
Pharm Res. 2024.
PMID: 38302834
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Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer.
Wang J, Wei J, Pu T, Zeng A, Karthikeyan V, Bechtold B, Vo K, Chen J, Lin TP, Chang AP, Corey E, Puhr M, Klocker H, Culig Z, Bland T, Wu BJ.
Wang J, et al. Among authors: bechtold b.
Cell Rep Med. 2024 Feb 20;5(2):101388. doi: 10.1016/j.xcrm.2023.101388. Epub 2024 Jan 22.
Cell Rep Med. 2024.
PMID: 38262412
Free PMC article.
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Rifampin- and Silymarin-Mediated Pharmacokinetic Interactions of Exogenous and Endogenous Substrates in a Transgenic OATP1B Mouse Model.
Bechtold BJ, Lynch KD, Oyanna VO, Call MR, Graf TN, Oberlies NH, Clarke JD.
Bechtold BJ, et al.
Mol Pharm. 2024 May 6;21(5):2284-2297. doi: 10.1021/acs.molpharmaceut.3c01088. Epub 2024 Mar 26.
Mol Pharm. 2024.
PMID: 38529622
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