MacRae JI - Search Results

1

Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia.

Grimm F, Asuaje A, Jain A, Silva Dos Santos M, Kleinjung J, Nunes PM, Gehrig S, Fets L, Darici S, MacRae JI, Anastasiou D. Grimm F, et al. Among authors: macrae ji. EMBO J. 2024 Apr;43(8):1545-1569. doi: 10.1038/s44318-024-00065-w. Epub 2024 Mar 14. EMBO J. 2024. PMID: 38485816 Free PMC article.

2

An engineered photoswitchable mammalian pyruvate kinase.

Gehrig S, Macpherson JA, Driscoll PC, Symon A, Martin SR, MacRae JI, Kleinjung J, Fraternali F, Anastasiou D. Gehrig S, et al. Among authors: macrae ji. FEBS J. 2017 Sep;284(18):2955-2980. doi: 10.1111/febs.14175. Epub 2017 Aug 16. FEBS J. 2017. PMID: 28715126 Free PMC article.

3

Metabolic oscillations on the circadian time scale in Drosophila cells lacking clock genes.

Rey G, Milev NB, Valekunja UK, Ch R, Ray S, Silva Dos Santos M, Nagy AD, Antrobus R, MacRae JI, Reddy AB. Rey G, et al. Among authors: macrae ji. Mol Syst Biol. 2018 Aug 2;14(8):e8376. doi: 10.15252/msb.20188376. Mol Syst Biol. 2018. PMID: 30072421 Free PMC article.

4

MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG.

Fets L, Driscoll PC, Grimm F, Jain A, Nunes PM, Gounis M, Doglioni G, Papageorgiou G, Ragan TJ, Campos S, Silva Dos Santos M, MacRae JI, O'Reilly N, Wright AJ, Benes CH, Courtney KD, House D, Anastasiou D. Fets L, et al. Among authors: macrae ji. Nat Chem Biol. 2018 Nov;14(11):1032-1042. doi: 10.1038/s41589-018-0136-y. Epub 2018 Oct 8. Nat Chem Biol. 2018. PMID: 30297875 Free PMC article.

5

Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells.

Haythorne E, Rohm M, van de Bunt M, Brereton MF, Tarasov AI, Blacker TS, Sachse G, Silva Dos Santos M, Terron Exposito R, Davis S, Baba O, Fischer R, Duchen MR, Rorsman P, MacRae JI, Ashcroft FM. Haythorne E, et al. Among authors: macrae ji. Nat Commun. 2019 Jun 6;10(1):2474. doi: 10.1038/s41467-019-10189-x. Nat Commun. 2019. PMID: 31171772 Free PMC article.

6

Author Correction: MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG.

Fets L, Driscoll PC, Grimm F, Jain A, Nunes PM, Gounis M, Doglioni G, Papageorgiou G, Ragan TJ, Campos S, Dos Santos MS, MacRae JI, O'Reilly N, Wright AJ, Benes CH, Courtney KD, House D, Anastasiou D. Fets L, et al. Among authors: macrae ji. Nat Chem Biol. 2019 Dec;15(12):1249. doi: 10.1038/s41589-019-0409-0. Nat Chem Biol. 2019. PMID: 31645751

7

Targeting the nucleotide salvage factor DNPH1 sensitizes BRCA-deficient cells to PARP inhibitors.

Fugger K, Bajrami I, Silva Dos Santos M, Young SJ, Kunzelmann S, Kelly G, Hewitt G, Patel H, Goldstone R, Carell T, Boulton SJ, MacRae J, Taylor IA, West SC. Fugger K, et al. Science. 2021 Apr 9;372(6538):156-165. doi: 10.1126/science.abb4542. Science. 2021. PMID: 33833118 Free PMC article.

8

MOG analogues to explore the MCT2 pharmacophore, α-ketoglutarate biology and cellular effects of N-oxalylglycine.

Fets L, Bevan N, Nunes PM, Campos S, Dos Santos MS, Sherriff E, MacRae JI, House D, Anastasiou D. Fets L, et al. Among authors: macrae ji. Commun Biol. 2022 Aug 26;5(1):877. doi: 10.1038/s42003-022-03805-y. Commun Biol. 2022. PMID: 36028752 Free PMC article.

9

Publisher Correction: MOG analogues to explore the MCT2 pharmacophore, α-ketoglutarate biology and cellular effects of N-oxalylglycine.

Fets L, Bevan N, Nunes PM, Campos S, Dos Santos MS, Sherriff E, MacRae JI, House D, Anastasiou D. Fets L, et al. Among authors: macrae ji. Commun Biol. 2022 Sep 27;5(1):1019. doi: 10.1038/s42003-022-03922-8. Commun Biol. 2022. PMID: 36167803 Free PMC article. No abstract available.

10

Mechanism of substrate hydrolysis by the human nucleotide pool sanitiser DNPH1.

Rzechorzek NJ, Kunzelmann S, Purkiss AG, Silva Dos Santos M, MacRae JI, Taylor IA, Fugger K, West SC. Rzechorzek NJ, et al. Among authors: macrae ji. Nat Commun. 2023 Oct 26;14(1):6809. doi: 10.1038/s41467-023-42544-4. Nat Commun. 2023. PMID: 37884503 Free PMC article.

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