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Comparative structure activity and target exploration of 1,2-diphenylethynes in Haemonchus contortus and Caenorhabditis elegans.
Int J Parasitol Drugs Drug Resist. 2024 Mar 19;25:100534. doi: 10.1016/j.ijpddr.2024.100534. Online ahead of print.
Int J Parasitol Drugs Drug Resist. 2024.
PMID: 38554597
Free PMC article.
A phenotypic screen of the Global Health Priority Box identifies an insecticide with anthelmintic activity.
Shanley HT, Taki AC, Byrne JJ, Nguyen N, Wells TNC, Jabbar A, Sleebs BE, Gasser RB.
Shanley HT, et al.
Parasit Vectors. 2024 Mar 14;17(1):131. doi: 10.1186/s13071-024-06183-y.
Parasit Vectors. 2024.
PMID: 38486232
Free PMC article.
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Structure-activity relationship and target investigation of 2-aryl quinolines with nematocidal activity.
Shanley HT, Taki AC, Nguyen N, Wang T, Byrne JJ, Ang CS, Leeming MG, Nie S, Williamson N, Zheng Y, Young ND, Korhonen PK, Hofmann A, Chang BCH, Wells TNC, Häberli C, Keiser J, Jabbar A, Sleebs BE, Gasser RB.
Shanley HT, et al.
Int J Parasitol Drugs Drug Resist. 2024 Apr;24:100522. doi: 10.1016/j.ijpddr.2024.100522. Epub 2024 Jan 23.
Int J Parasitol Drugs Drug Resist. 2024.
PMID: 38295619
Free PMC article.
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Structure activity relationship and target prediction for ABX464 analogues in Caenorhabditis elegans.
Shanley HT, Taki AC, Nguyen N, Wang T, Byrne JJ, Ang CS, Leeming MG, Nie S, Williamson N, Zheng Y, Young ND, Korhonen PK, Hofmann A, Wells TNC, Jabbar A, Sleebs BE, Gasser RB.
Shanley HT, et al.
Bioorg Med Chem. 2024 Jan 15;98:117540. doi: 10.1016/j.bmc.2023.117540. Epub 2023 Dec 3.
Bioorg Med Chem. 2024.
PMID: 38134663
Free article.
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A High-Throughput Phenotypic Screen of the 'Pandemic Response Box' Identifies a Quinoline Derivative with Significant Anthelmintic Activity.
Shanley HT, Taki AC, Byrne JJ, Jabbar A, Wells TNC, Samby K, Boag PR, Nguyen N, Sleebs BE, Gasser RB.
Shanley HT, et al.
Pharmaceuticals (Basel). 2022 Feb 21;15(2):257. doi: 10.3390/ph15020257.
Pharmaceuticals (Basel). 2022.
PMID: 35215369
Free PMC article.
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