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First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure.
Zwirner S, Abu Rmilah AA, Klotz S, Pfaffenroth B, Kloevekorn P, Moschopoulou AA, Schuette S, Haag M, Selig R, Li K, Zhou W, Nelson E, Poso A, Chen H, Amiot B, Jia Y, Minshew A, Michalak G, Cui W, Rist E, Longerich T, Jung B, Felgendreff P, Trompak O, Premsrirut PK, Gries K, Muerdter TE, Heinkele G, Wuestefeld T, Shapiro D, Weissbach M, Koenigsrainer A, Sipos B, Ab E, Zacarias MO, Theisgen S, Gruenheit N, Biskup S, Schwab M, Albrecht W, Laufer S, Nyberg S, Zender L. Zwirner S, et al. Among authors: gruenheit n. Cell. 2024 Mar 28;187(7):1666-1684.e26. doi: 10.1016/j.cell.2024.02.023. Epub 2024 Mar 14. Cell. 2024. PMID: 38490194 Free PMC article. Clinical Trial.
Conditional expression explains molecular evolution of social genes in a microbe.
de Oliveira JL, Morales AC, Stewart B, Gruenheit N, Engelmoer J, Brown SB, de Brito RA, Hurst LD, Urrutia AO, Thompson CRL, Wolf JB. de Oliveira JL, et al. Among authors: gruenheit n. Nat Commun. 2019 Jul 23;10(1):3284. doi: 10.1038/s41467-019-11237-2. Nat Commun. 2019. PMID: 31337766 Free PMC article.
Cell Cycle Heterogeneity Can Generate Robust Cell Type Proportioning.
Gruenheit N, Parkinson K, Brimson CA, Kuwana S, Johnson EJ, Nagayama K, Llewellyn J, Salvidge WM, Stewart B, Keller T, van Zon W, Cotter SL, Thompson CRL. Gruenheit N, et al. Dev Cell. 2018 Nov 19;47(4):494-508.e4. doi: 10.1016/j.devcel.2018.09.023. Epub 2018 Oct 25. Dev Cell. 2018. PMID: 30473004 Free PMC article.
Fitness Trade-offs Result in the Illusion of Social Success.
Wolf JB, Howie JA, Parkinson K, Gruenheit N, Melo D, Rozen D, Thompson CR. Wolf JB, et al. Among authors: gruenheit n. Curr Biol. 2015 Apr 20;25(8):1086-90. doi: 10.1016/j.cub.2015.02.061. Epub 2015 Mar 26. Curr Biol. 2015. PMID: 25819562 Free PMC article.
19 results