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A mechanistic model of primer synthesis from catalytic structures of DNA polymerase α-primase.
Nat Struct Mol Biol. 2024 May;31(5):777-790. doi: 10.1038/s41594-024-01227-4. Epub 2024 Mar 15.
Nat Struct Mol Biol. 2024.
PMID: 38491139
Structure of a DNA glycosylase that unhooks interstrand cross-links.
Mullins EA, Warren GM, Bradley NP, Eichman BF.
Mullins EA, et al. Among authors: bradley np.
Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4400-4405. doi: 10.1073/pnas.1703066114. Epub 2017 Apr 10.
Proc Natl Acad Sci U S A. 2017.
PMID: 28396405
Free PMC article.
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A mechanistic model of primer synthesis from catalytic structures of DNA polymerase α-primase.
Mullins EA, Salay LE, Durie CL, Bradley NP, Jackman JE, Ohi MD, Chazin WJ, Eichman BF.
Mullins EA, et al. Among authors: bradley np.
bioRxiv [Preprint]. 2023 Sep 28:2023.03.16.533013. doi: 10.1101/2023.03.16.533013.
bioRxiv. 2023.
PMID: 36993335
Free PMC article.
Updated.
Preprint.
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Emerging Roles of DNA Glycosylases and the Base Excision Repair Pathway.
Mullins EA, Rodriguez AA, Bradley NP, Eichman BF.
Mullins EA, et al. Among authors: bradley np.
Trends Biochem Sci. 2019 Sep;44(9):765-781. doi: 10.1016/j.tibs.2019.04.006. Epub 2019 May 9.
Trends Biochem Sci. 2019.
PMID: 31078398
Free PMC article.
Review.
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Escherichia coli YcaQ is a DNA glycosylase that unhooks DNA interstrand crosslinks.
Bradley NP, Washburn LA, Christov PP, Watanabe CMH, Eichman BF.
Bradley NP, et al.
Nucleic Acids Res. 2020 Jul 27;48(13):7005-7017. doi: 10.1093/nar/gkaa346.
Nucleic Acids Res. 2020.
PMID: 32409837
Free PMC article.
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Resistance-Guided Mining of Bacterial Genotoxins Defines a Family of DNA Glycosylases.
Bradley NP, Wahl KL, Steenwyk JL, Rokas A, Eichman BF.
Bradley NP, et al.
mBio. 2022 Apr 26;13(2):e0329721. doi: 10.1128/mbio.03297-21. Epub 2022 Mar 21.
mBio. 2022.
PMID: 35311535
Free PMC article.
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Base excision repair system targeting DNA adducts of trioxacarcin/LL-D49194 antibiotics for self-resistance.
Chen X, Bradley NP, Lu W, Wahl KL, Zhang M, Yuan H, Hou XF, Eichman BF, Tang GL.
Chen X, et al. Among authors: bradley np.
Nucleic Acids Res. 2022 Mar 21;50(5):2417-2430. doi: 10.1093/nar/gkac085.
Nucleic Acids Res. 2022.
PMID: 35191495
Free PMC article.
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Extensive loss of cell-cycle and DNA repair genes in an ancient lineage of bipolar budding yeasts.
Steenwyk JL, Opulente DA, Kominek J, Shen XX, Zhou X, Labella AL, Bradley NP, Eichman BF, Čadež N, Libkind D, DeVirgilio J, Hulfachor AB, Kurtzman CP, Hittinger CT, Rokas A.
Steenwyk JL, et al. Among authors: bradley np.
PLoS Biol. 2019 May 21;17(5):e3000255. doi: 10.1371/journal.pbio.3000255. eCollection 2019 May.
PLoS Biol. 2019.
PMID: 31112549
Free PMC article.
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