Salay LE - Search Results

1

A mechanistic model of primer synthesis from catalytic structures of DNA polymerase α-primase.

Mullins EA, Salay LE, Durie CL, Bradley NP, Jackman JE, Ohi MD, Chazin WJ, Eichman BF. Mullins EA, et al. Among authors: salay le. Nat Struct Mol Biol. 2024 May;31(5):777-790. doi: 10.1038/s41594-024-01227-4. Epub 2024 Mar 15. Nat Struct Mol Biol. 2024. PMID: 38491139

2

Flexibility and distributive synthesis regulate RNA priming and handoff in human DNA polymerase α-primase.

Cordoba JJ, Mullins EA, Salay LE, Eichman BF, Chazin WJ. Cordoba JJ, et al. Among authors: salay le. bioRxiv [Preprint]. 2023 Aug 1:2023.08.01.551538. doi: 10.1101/2023.08.01.551538. bioRxiv. 2023. PMID: 37577606 Free PMC article. Updated. Preprint.

3

Flexibility and Distributive Synthesis Regulate RNA Priming and Handoff in Human DNA Polymerase α-Primase.

Cordoba JJ, Mullins EA, Salay LE, Eichman BF, Chazin WJ. Cordoba JJ, et al. Among authors: salay le. J Mol Biol. 2023 Dec 15;435(24):168330. doi: 10.1016/j.jmb.2023.168330. Epub 2023 Oct 24. J Mol Biol. 2023. PMID: 37884206

4

The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport.

O'Brien E, Holt ME, Thompson MK, Salay LE, Ehlinger AC, Chazin WJ, Barton JK. O'Brien E, et al. Among authors: salay le. Science. 2017 Feb 24;355(6327):eaag1789. doi: 10.1126/science.aag1789. Science. 2017. PMID: 28232525 Free PMC article.

5

A Polymerase With Potential: The Fe-S Cluster in Human DNA Primase.

Holt ME, Salay LE, Chazin WJ. Holt ME, et al. Among authors: salay le. Methods Enzymol. 2017;595:361-390. doi: 10.1016/bs.mie.2017.07.002. Epub 2017 Aug 18. Methods Enzymol. 2017. PMID: 28882207

6

Substrate Binding Regulates Redox Signaling in Human DNA Primase.

O'Brien E, Holt ME, Salay LE, Chazin WJ, Barton JK. O'Brien E, et al. Among authors: salay le. J Am Chem Soc. 2018 Dec 12;140(49):17153-17162. doi: 10.1021/jacs.8b09914. Epub 2018 Nov 29. J Am Chem Soc. 2018. PMID: 30433774 Free PMC article.

7

Functional and structural similarity of human DNA primase [4Fe4S] cluster domain constructs.

Holt ME, Salay LE, O'Brien E, Barton JK, Chazin WJ. Holt ME, et al. Among authors: salay le. PLoS One. 2018 Dec 18;13(12):e0209345. doi: 10.1371/journal.pone.0209345. eCollection 2018. PLoS One. 2018. PMID: 30562384 Free PMC article.

8

Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.

Salay LE, Blee AM, Raza MK, Gallagher KS, Chen H, Dorfeuille AJ, Barton JK, Chazin WJ. Salay LE, et al. Biochemistry. 2022 Jun 7;61(11):1113-1123. doi: 10.1021/acs.biochem.2c00100. Epub 2022 May 26. Biochemistry. 2022. PMID: 35617695 Free PMC article.

9

A mechanistic model of primer synthesis from catalytic structures of DNA polymerase α-primase.

Mullins EA, Salay LE, Durie CL, Bradley NP, Jackman JE, Ohi MD, Chazin WJ, Eichman BF. Mullins EA, et al. Among authors: salay le. bioRxiv [Preprint]. 2023 Sep 28:2023.03.16.533013. doi: 10.1101/2023.03.16.533013. bioRxiv. 2023. PMID: 36993335 Free PMC article. Updated. Preprint.

10

Response to Comments on "The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport".

O'Brien E, Holt ME, Thompson MK, Salay LE, Ehlinger AC, Chazin WJ, Barton JK. O'Brien E, et al. Among authors: salay le. Science. 2017 Jul 21;357(6348):eaan2762. doi: 10.1126/science.aan2762. Science. 2017. PMID: 28729485 Free PMC article.

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