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STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade.
Fu J, Kanne DB, Leong M, Glickman LH, McWhirter SM, Lemmens E, Mechette K, Leong JJ, Lauer P, Liu W, Sivick KE, Zeng Q, Soares KC, Zheng L, Portnoy DA, Woodward JJ, Pardoll DM, Dubensky TW Jr, Kim Y. Fu J, et al. Among authors: zheng l. Sci Transl Med. 2015 Apr 15;7(283):283ra52. doi: 10.1126/scitranslmed.aaa4306. Sci Transl Med. 2015. PMID: 25877890 Free PMC article.
Cancer-Associated Fibroblasts in Pancreatic Cancer Are Reprogrammed by Tumor-Induced Alterations in Genomic DNA Methylation.
Xiao Q, Zhou D, Rucki AA, Williams J, Zhou J, Mo G, Murphy A, Fujiwara K, Kleponis J, Salman B, Wolfgang CL, Anders RA, Zheng S, Jaffee EM, Zheng L. Xiao Q, et al. Among authors: zheng s, zheng l. Cancer Res. 2016 Sep 15;76(18):5395-404. doi: 10.1158/0008-5472.CAN-15-3264. Epub 2016 Aug 5. Cancer Res. 2016. PMID: 27496707 Free PMC article.
DNA methylation in the tumor microenvironment.
Zhang MW, Fujiwara K, Che X, Zheng S, Zheng L. Zhang MW, et al. Among authors: zheng s, zheng l. J Zhejiang Univ Sci B. 2017 May;18(5):365-372. doi: 10.1631/jzus.B1600579. J Zhejiang Univ Sci B. 2017. PMID: 28471108 Free PMC article. Review.
Is a Pathological Complete Response Following Neoadjuvant Chemoradiation Associated With Prolonged Survival in Patients With Pancreatic Cancer?
He J, Blair AB, Groot VP, Javed AA, Burkhart RA, Gemenetzis G, Hruban RH, Waters KM, Poling J, Zheng L, Laheru D, Herman JM, Makary MA, Weiss MJ, Cameron JL, Wolfgang CL. He J, et al. Among authors: zheng l. Ann Surg. 2018 Jul;268(1):1-8. doi: 10.1097/SLA.0000000000002672. Ann Surg. 2018. PMID: 29334562 Free PMC article.
Immune defects in pancreatic cancer.
Zheng L. Zheng L. Ann Pancreat Cancer. 2018 Dec;1:33. doi: 10.21037/apc.2018.11.01. Epub 2018 Dec 6. Ann Pancreat Cancer. 2018. PMID: 30613834 Free PMC article.
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