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Precision Enhancement of CAR-NK Cells through Non-Viral Engineering and Highly Multiplexed Base Editing.
Wang M, Krueger JB, Gilkey AK, Stelljes EM, Kluesner MG, Pomeroy EJ, Skeate JG, Slipek NJ, Lahr WS, Vázquez PNC, Zhao Y, Eaton EJ, Laoharawee K, Webber BR, Moriarity BS. Wang M, et al. Among authors: kluesner mg. bioRxiv [Preprint]. 2024 Mar 8:2024.03.05.582637. doi: 10.1101/2024.03.05.582637. bioRxiv. 2024. PMID: 38496503 Free PMC article. Preprint.
Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks.
Jaeger-Ruckstuhl CA, Lo Y, Fulton E, Waltner OG, Shabaneh TB, Simon S, Muthuraman PV, Correnti CE, Newsom OJ, Engstrom IA, Kanaan SB, Bhise SS, Peralta JMC, Ruff R, Price JP, Stull SM, Stevens AR, Bugos G, Kluesner MG, Voillet V, Muhunthan V, Morrish F, Olson JM, Gottardo R, Sarthy JF, Henikoff S, Sullivan LB, Furlan SN, Riddell SR. Jaeger-Ruckstuhl CA, et al. Among authors: kluesner mg. Immunity. 2024 Feb 13;57(2):287-302.e12. doi: 10.1016/j.immuni.2024.01.011. Immunity. 2024. PMID: 38354704 Free article.
Correction of Fanconi Anemia Mutations Using Digital Genome Engineering.
Sipe CJ, Kluesner MG, Bingea SP, Lahr WS, Andrew AA, Wang M, DeFeo AP, Hinkel TL, Laoharawee K, Wagner JE, MacMillan ML, Vercellotti GM, Tolar J, Osborn MJ, McIvor RS, Webber BR, Moriarity BS. Sipe CJ, et al. Among authors: kluesner mg. Int J Mol Sci. 2022 Jul 29;23(15):8416. doi: 10.3390/ijms23158416. Int J Mol Sci. 2022. PMID: 35955545 Free PMC article.
CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells.
Kluesner MG, Lahr WS, Lonetree CL, Smeester BA, Qiu X, Slipek NJ, Claudio Vázquez PN, Pitzen SP, Pomeroy EJ, Vignes MJ, Lee SC, Bingea SP, Andrew AA, Webber BR, Moriarity BS. Kluesner MG, et al. Nat Commun. 2021 Apr 23;12(1):2437. doi: 10.1038/s41467-021-22009-2. Nat Commun. 2021. PMID: 33893286 Free PMC article.
Author Correction: Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors.
Webber BR, Lonetree CL, Kluesner MG, Johnson MJ, Pomeroy EJ, Diers MD, Lahr WS, Draper GM, Slipek NJ, Smeester BA, Lovendahl KN, McElroy AN, Gordon WR, Osborn MJ, Moriarity BS. Webber BR, et al. Among authors: kluesner mg. Nat Commun. 2019 Dec 6;10(1):5659. doi: 10.1038/s41467-019-13778-y. Nat Commun. 2019. PMID: 31811147 Free PMC article.
A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy.
Pomeroy EJ, Hunzeker JT, Kluesner MG, Lahr WS, Smeester BA, Crosby MR, Lonetree CL, Yamamoto K, Bendzick L, Miller JS, Geller MA, Walcheck B, Felices M, Webber BR, Starr TK, Moriarity BS. Pomeroy EJ, et al. Among authors: kluesner mg. Mol Ther. 2020 Jan 8;28(1):52-63. doi: 10.1016/j.ymthe.2019.10.009. Epub 2019 Oct 15. Mol Ther. 2020. PMID: 31704085 Free PMC article.
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