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Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays.
Kurata M, Wolf NK, Lahr WS, Weg MT, Kluesner MG, Lee S, Hui K, Shiraiwa M, Webber BR, Moriarity BS. Kurata M, et al. Among authors: webber br. PLoS One. 2018 Sep 17;13(9):e0198714. doi: 10.1371/journal.pone.0198714. eCollection 2018. PLoS One. 2018. PMID: 30222773 Free PMC article.
EditR: A Method to Quantify Base Editing from Sanger Sequencing.
Kluesner MG, Nedveck DA, Lahr WS, Garbe JR, Abrahante JE, Webber BR, Moriarity BS. Kluesner MG, et al. Among authors: webber br. CRISPR J. 2018 Jun;1(3):239-250. doi: 10.1089/crispr.2018.0014. CRISPR J. 2018. PMID: 31021262 Free PMC article.
A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy.
Pomeroy EJ, Hunzeker JT, Kluesner MG, Lahr WS, Smeester BA, Crosby MR, Lonetree CL, Yamamoto K, Bendzick L, Miller JS, Geller MA, Walcheck B, Felices M, Webber BR, Starr TK, Moriarity BS. Pomeroy EJ, et al. Among authors: webber br. Mol Ther. 2020 Jan 8;28(1):52-63. doi: 10.1016/j.ymthe.2019.10.009. Epub 2019 Oct 15. Mol Ther. 2020. PMID: 31704085 Free PMC article.
Genome Engineering of Primary Human B Cells Using CRISPR/Cas9.
Laoharawee K, Johnson MJ, Lahr WS, Peterson JJ, Webber BR, Moriarity BS. Laoharawee K, et al. Among authors: webber br. J Vis Exp. 2020 Nov 3;(165):10.3791/61855. doi: 10.3791/61855. J Vis Exp. 2020. PMID: 33226023 Free PMC article.
CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells.
Kluesner MG, Lahr WS, Lonetree CL, Smeester BA, Qiu X, Slipek NJ, Claudio Vázquez PN, Pitzen SP, Pomeroy EJ, Vignes MJ, Lee SC, Bingea SP, Andrew AA, Webber BR, Moriarity BS. Kluesner MG, et al. Among authors: webber br. Nat Commun. 2021 Apr 23;12(1):2437. doi: 10.1038/s41467-021-22009-2. Nat Commun. 2021. PMID: 33893286 Free PMC article.
Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments.
Tabdanov ED, Rodríguez-Merced NJ, Cartagena-Rivera AX, Puram VV, Callaway MK, Ensminger EA, Pomeroy EJ, Yamamoto K, Lahr WS, Webber BR, Moriarity BS, Zhovmer AS, Provenzano PP. Tabdanov ED, et al. Among authors: webber br. Nat Commun. 2021 May 14;12(1):2815. doi: 10.1038/s41467-021-22985-5. Nat Commun. 2021. PMID: 33990566 Free PMC article.
51 results