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KRAS4b:RAF-1 Homogenous Time-Resolved Fluorescence Resonance Energy Transfer Assay for Drug Discovery.
Methods Mol Biol. 2024;2797:159-175. doi: 10.1007/978-1-0716-3822-4_12.
Methods Mol Biol. 2024.
PMID: 38570459
Measurement of KRAS-GTPase Activity.
Rabara D, Stephen AG.
Rabara D, et al.
Methods Mol Biol. 2024;2797:91-102. doi: 10.1007/978-1-0716-3822-4_7.
Methods Mol Biol. 2024.
PMID: 38570454
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A Top-Down Proteomic Assay to Evaluate KRAS4B-Compound Engagement.
D'Ippolito RA, Rabara D, Blanco MA, Alberico E, Drew MR, Ramakrishnan N, Sontan D, Widmeyer SRT, Scheidemantle GM, Messing S, Turner D, Arkin M, Maciag AE, Stephen AG, Esposito D, McCormick F, Nissley DV, DeHart CJ.
D'Ippolito RA, et al. Among authors: rabara d.
Anal Chem. 2024 Apr 2;96(13):5223-5231. doi: 10.1021/acs.analchem.3c05626. Epub 2024 Mar 18.
Anal Chem. 2024.
PMID: 38498381
Free PMC article.
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Revealing the mechanism of action of a first-in-class covalent inhibitor of KRASG12C (ON) and other functional properties of oncogenic KRAS by 31P NMR.
Sharma AK, Pei J, Yang Y, Dyba M, Smith B, Rabara D, Larsen EK, Lightstone FC, Esposito D, Stephen AG, Wang B, Beltran PJ, Wallace E, Nissley DV, McCormick F, Maciag AE.
Sharma AK, et al. Among authors: rabara d.
J Biol Chem. 2024 Feb;300(2):105650. doi: 10.1016/j.jbc.2024.105650. Epub 2024 Jan 16.
J Biol Chem. 2024.
PMID: 38237681
Free PMC article.
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Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer.
Sherekar M, Han SW, Ghirlando R, Messing S, Drew M, Rabara D, Waybright T, Juneja P, O'Neill H, Stanley CB, Bhowmik D, Ramanathan A, Subramaniam S, Nissley DV, Gillette W, McCormick F, Esposito D.
Sherekar M, et al. Among authors: rabara d.
J Biol Chem. 2020 Jan 24;295(4):1105-1119. doi: 10.1074/jbc.RA119.010934. Epub 2019 Dec 13.
J Biol Chem. 2020.
PMID: 31836666
Free PMC article.
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KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis.
Rabara D, Tran TH, Dharmaiah S, Stephens RM, McCormick F, Simanshu DK, Holderfield M.
Rabara D, et al.
Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22122-22131. doi: 10.1073/pnas.1908353116. Epub 2019 Oct 14.
Proc Natl Acad Sci U S A. 2019.
PMID: 31611389
Free PMC article.
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Label-Free Time-Gated Luminescent Detection Method for the Nucleotides with Varying Phosphate Content.
Kopra K, Seppälä T, Rabara D, Abreu-Blanco M, Kulmala S, Holderfield M, Härmä H.
Kopra K, et al. Among authors: rabara d.
Sensors (Basel). 2018 Nov 16;18(11):3989. doi: 10.3390/s18113989.
Sensors (Basel). 2018.
PMID: 30453509
Free PMC article.
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