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Synthesis of bioengineered heparin chemically and biologically similar to porcine-derived products and convertible to low MW heparin.
Douaisi M, Paskaleva EE, Fu L, Grover N, McManaman CL, Varghese S, Brodfuehrer PR, Gibson JM, de Joode I, Xia K, Brier MI, Simmons TJ, Datta P, Zhang F, Onishi A, Hirakane M, Mori D, Linhardt RJ, Dordick JS. Douaisi M, et al. Among authors: gibson jm. Proc Natl Acad Sci U S A. 2024 Apr 2;121(14):e2315586121. doi: 10.1073/pnas.2315586121. Epub 2024 Mar 18. Proc Natl Acad Sci U S A. 2024. PMID: 38498726
3-O-Sulfation of Heparan Sulfate Enhances Tau Interaction and Cellular Uptake.
Zhao J, Zhu Y, Song X, Xiao Y, Su G, Liu X, Wang Z, Xu Y, Liu J, Eliezer D, Ramlall TF, Lippens G, Gibson J, Zhang F, Linhardt RJ, Wang L, Wang C. Zhao J, et al. Angew Chem Int Ed Engl. 2020 Jan 27;59(5):1818-1827. doi: 10.1002/anie.201913029. Epub 2019 Dec 10. Angew Chem Int Ed Engl. 2020. PMID: 31692167 Free PMC article.
Covalent fragment inhibits intramembrane proteolysis.
Eden A, Zhao J, Xiao Y, Gibson J, Wang C. Eden A, et al. Front Mol Biosci. 2022 Sep 7;9:958399. doi: 10.3389/fmolb.2022.958399. eCollection 2022. Front Mol Biosci. 2022. PMID: 36158579 Free PMC article.
Inhibition of Staphylococcus aureus biofilm-forming functional amyloid by molecular tweezers.
Malishev R, Salinas N, Gibson J, Eden AB, Mieres-Perez J, Ruiz-Blanco YB, Malka O, Kolusheva S, Klärner FG, Schrader T, Sanchez-Garcia E, Wang C, Landau M, Bitan G, Jelinek R. Malishev R, et al. Cell Chem Biol. 2021 Sep 16;28(9):1310-1320.e5. doi: 10.1016/j.chembiol.2021.03.013. Epub 2021 Apr 13. Cell Chem Biol. 2021. PMID: 33852903 Free PMC article.
Research gaps and priorities for quantitative microbial risk assessment (QMRA).
Hamilton KA, Ciol Harrison J, Mitchell J, Weir M, Verhougstraete M, Haas CN, Nejadhashemi AP, Libarkin J, Gim Aw T, Bibby K, Bivins A, Brown J, Dean K, Dunbar G, Eisenberg JNS, Emelko M, Gerrity D, Gurian PL, Hartnett E, Jahne M, Jones RM, Julian TR, Li H, Li Y, Gibson JM, Medema G, Meschke JS, Mraz A, Murphy H, Oryang D, Owusu-Ansah EDJ, Pasek E, Pradhan AK, Razzolini MTP, Ryan MO, Schoen M, Smeets PWMH, Soller J, Solo-Gabriele H, Williams C, Wilson AM, Zimmer-Faust A, Alja'fari J, Rose JB. Hamilton KA, et al. Among authors: gibson jm. Risk Anal. 2024 May 21. doi: 10.1111/risa.14318. Online ahead of print. Risk Anal. 2024. PMID: 38772724
449 results