Tarafdar A - Search Results

1

The parasitic worm product ES-62 protects against collagen-induced arthritis by resetting the gut-bone marrow axis in a microbiome-dependent manner.

Harnett MM, Doonan J, Tarafdar A, Pineda MA, Duncombe-Moore J, Buitrago G, Pan P, Hoskisson PA, Selman C, Harnett W. Harnett MM, et al. Among authors: tarafdar a. Front Trop Dis. 2024 Jan 31;4:fitd.2023.1334705. doi: 10.3389/fitd.2023.1334705. Front Trop Dis. 2024. PMID: 38500783 Free PMC article.

2

Protection Against Arthritis by the Parasitic Worm Product ES-62, and Its Drug-Like Small Molecule Analogues, Is Associated With Inhibition of Osteoclastogenesis.

Doonan J, Lumb FE, Pineda MA, Tarafdar A, Crowe J, Khan AM, Suckling CJ, Harnett MM, Harnett W. Doonan J, et al. Among authors: tarafdar a. Front Immunol. 2018 May 14;9:1016. doi: 10.3389/fimmu.2018.01016. eCollection 2018. Front Immunol. 2018. PMID: 29867986 Free PMC article.

3

The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis.

Doonan J, Tarafdar A, Pineda MA, Lumb FE, Crowe J, Khan AM, Hoskisson PA, Harnett MM, Harnett W. Doonan J, et al. Among authors: tarafdar a. Nat Commun. 2019 Apr 5;10(1):1554. doi: 10.1038/s41467-019-09361-0. Nat Commun. 2019. PMID: 30952846 Free PMC article.

4

The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing.

Crowe J, Lumb FE, Doonan J, Broussard M, Tarafdar A, Pineda MA, Landabaso C, Mulvey L, Hoskisson PA, Babayan SA, Selman C, Harnett W, Harnett MM. Crowe J, et al. Among authors: tarafdar a. PLoS Pathog. 2020 Mar 12;16(3):e1008391. doi: 10.1371/journal.ppat.1008391. eCollection 2020 Mar. PLoS Pathog. 2020. PMID: 32163524 Free PMC article.

5

Suppression of inflammatory arthritis by the parasitic worm product ES-62 is associated with epigenetic changes in synovial fibroblasts.

Corbet M, Pineda MA, Yang K, Tarafdar A, McGrath S, Nakagawa R, Lumb FE, Suckling CJ, Harnett W, Harnett MM. Corbet M, et al. Among authors: tarafdar a. PLoS Pathog. 2021 Nov 8;17(11):e1010069. doi: 10.1371/journal.ppat.1010069. eCollection 2021 Nov. PLoS Pathog. 2021. PMID: 34748611 Free PMC article.

6

CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression.

Tarafdar A, Hopcroft LE, Gallipoli P, Pellicano F, Cassels J, Hair A, Korfi K, Jørgensen HG, Vetrie D, Holyoake TL, Michie AM. Tarafdar A, et al. Blood. 2017 Jan 12;129(2):199-208. doi: 10.1182/blood-2016-09-742049. Epub 2016 Oct 28. Blood. 2017. PMID: 27793879 Free PMC article.

7

Canonical Wnt signaling promotes early hematopoietic progenitor formation and erythroid specification during embryonic stem cell differentiation.

Tarafdar A, Dobbin E, Corrigan P, Freeburn R, Wheadon H. Tarafdar A, et al. PLoS One. 2013 Nov 26;8(11):e81030. doi: 10.1371/journal.pone.0081030. eCollection 2013. PLoS One. 2013. PMID: 24324557 Free PMC article.

8

AKT/mTORC2 Inhibition Activates FOXO1 Function in CLL Cells Reducing B-Cell Receptor-Mediated Survival.

Cosimo E, Tarafdar A, Moles MW, Holroyd AK, Malik N, Catherwood MA, Hay J, Dunn KM, Macdonald AM, Guichard SM, O'Rourke D, Leach MT, Sansom OJ, Cosulich SC, McCaig AM, Michie AM. Cosimo E, et al. Among authors: tarafdar a. Clin Cancer Res. 2019 Mar 1;25(5):1574-1587. doi: 10.1158/1078-0432.CCR-18-2036. Epub 2018 Dec 17. Clin Cancer Res. 2019. PMID: 30559170 Free PMC article.

9

PKCβ Facilitates Leukemogenesis in Chronic Lymphocytic Leukaemia by Promoting Constitutive BCR-Mediated Signalling.

Hay J, Tarafdar A, Holroyd AK, Moka HA, Dunn KM, Alshayeb A, Lloyd BH, Cassels J, Malik N, Khan AF, Sou I, Lees J, Almuhanna HNB, Kalakonda N, Slupsky JR, Michie AM. Hay J, et al. Among authors: tarafdar a. Cancers (Basel). 2022 Dec 6;14(23):6006. doi: 10.3390/cancers14236006. Cancers (Basel). 2022. PMID: 36497487 Free PMC article.

10

Generation of a poor prognostic chronic lymphocytic leukemia-like disease model: PKCα subversion induces up-regulation of PKCβII expression in B lymphocytes.

Nakagawa R, Vukovic M, Tarafdar A, Cosimo E, Dunn K, McCaig AM, Holroyd A, McClanahan F, Ramsay AG, Gribben JG, Michie AM. Nakagawa R, et al. Among authors: tarafdar a. Haematologica. 2015 Apr;100(4):499-510. doi: 10.3324/haematol.2014.112276. Epub 2015 Jan 23. Haematologica. 2015. PMID: 25616575 Free PMC article.

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