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Epigenetic modulators link mitochondrial redox homeostasis to cardiac function in a sex-dependent manner.
ElBeck Z, Hossain MB, Siga H, Oskolkov N, Karlsson F, Lindgren J, Walentinsson A, Koppenhöfer D, Jarvis R, Bürli R, Jamier T, Franssen E, Firth M, Degasperi A, Bendtsen C, Menzies RI, Streckfuss-Bömeke K, Kohlhaas M, Nickel AG, Lund LH, Maack C, Végvári Á, Betsholtz C. ElBeck Z, et al. Among authors: walentinsson a. Nat Commun. 2024 Mar 20;15(1):2358. doi: 10.1038/s41467-024-46384-8. Nat Commun. 2024. PMID: 38509128 Free PMC article.
Rare variant associations with plasma protein levels in the UK Biobank.
Dhindsa RS, Burren OS, Sun BB, Prins BP, Matelska D, Wheeler E, Mitchell J, Oerton E, Hristova VA, Smith KR, Carss K, Wasilewski S, Harper AR, Paul DS, Fabre MA, Runz H, Viollet C, Challis B, Platt A; AstraZeneca Genomics Initiative; Vitsios D, Ashley EA, Whelan CD, Pangalos MN, Wang Q, Petrovski S. Dhindsa RS, et al. Nature. 2023 Oct;622(7982):339-347. doi: 10.1038/s41586-023-06547-x. Epub 2023 Oct 4. Nature. 2023. PMID: 37794183 Free PMC article.
Vascular endothelial growth factor-D plasma levels and VEGFD genetic variants are independently associated with outcomes in patients with cardiovascular disease.
Davidsson P, Eketjäll S, Eriksson N, Walentinsson A, Becker RC, Cavallin A, Bogstedt A, Collén A, Held C, James S, Siegbahn A, Stewart R, Storey RF, White H, Wallentin L. Davidsson P, et al. Among authors: walentinsson a. Cardiovasc Res. 2023 Jul 4;119(7):1596-1605. doi: 10.1093/cvr/cvad039. Cardiovasc Res. 2023. PMID: 36869765
A Combined Human in Silico and CRISPR/Cas9-Mediated in Vivo Zebrafish Based Approach to Provide Phenotypic Data for Supporting Early Target Validation.
Winter MJ, Ono Y, Ball JS, Walentinsson A, Michaelsson E, Tochwin A, Scholpp S, Tyler CR, Rees S, Hetheridge MJ, Bohlooly-Y M. Winter MJ, et al. Among authors: walentinsson a. Front Pharmacol. 2022 Apr 25;13:827686. doi: 10.3389/fphar.2022.827686. eCollection 2022. Front Pharmacol. 2022. PMID: 35548346 Free PMC article.
Unraveling the Metabolic Derangements Occurring in Non-infarcted Areas of Pig Hearts With Chronic Heart Failure.
Correia C, Wang QD, Linhardt G, Carlsson LG, Ulfenborg B, Walentinsson A, Rydén-Markinhutha K, Behrendt M, Wikström J, Sartipy P, Jennbacken K, Synnergren J. Correia C, et al. Among authors: walentinsson a. Front Cardiovasc Med. 2021 Oct 13;8:753470. doi: 10.3389/fcvm.2021.753470. eCollection 2021. Front Cardiovasc Med. 2021. PMID: 34722683 Free PMC article.
Rare variant contribution to human disease in 281,104 UK Biobank exomes.
Wang Q, Dhindsa RS, Carss K, Harper AR, Nag A, Tachmazidou I, Vitsios D, Deevi SVV, Mackay A, Muthas D, Hühn M, Monkley S, Olsson H; AstraZeneca Genomics Initiative; Wasilewski S, Smith KR, March R, Platt A, Haefliger C, Petrovski S. Wang Q, et al. Nature. 2021 Sep;597(7877):527-532. doi: 10.1038/s41586-021-03855-y. Epub 2021 Aug 10. Nature. 2021. PMID: 34375979 Free PMC article.
MCPIP1 is a novel link between diabetogenic conditions and impaired insulin secretory capacity.
Tyka K, Jörns A, Dunst A, Tang Y, Bryde TH, Mehmeti I, Walentinsson A, Marselli L, Cnop M, Tyrberg B, Marzec MT, Gurgul-Convey E. Tyka K, et al. Among authors: walentinsson a. Biochim Biophys Acta Mol Basis Dis. 2021 Oct 1;1867(10):166199. doi: 10.1016/j.bbadis.2021.166199. Epub 2021 Jun 16. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 34144091 Free article.
Vasculoprotective properties of plasma lipoproteins from brown bears (Ursus arctos).
Pedrelli M, Parini P, Kindberg J, Arnemo JM, Bjorkhem I, Aasa U, Westerståhl M, Walentinsson A, Pavanello C, Turri M, Calabresi L, Öörni K, Camejo G, Fröbert O, Hurt-Camejo E. Pedrelli M, et al. Among authors: walentinsson a. J Lipid Res. 2021;62:100065. doi: 10.1016/j.jlr.2021.100065. Epub 2021 Mar 11. J Lipid Res. 2021. PMID: 33713671 Free PMC article.
30 results