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Francisella tularensis Live Vaccine Strain deficient in capB and overexpressing the fusion protein of IglA, IglB, and IglC from the bfr promoter induces improved protection against F. tularensis respiratory challenge.
Jia Q, Bowen R, Lee BY, Dillon BJ, Masleša-Galić S, Horwitz MA. Jia Q, et al. Among authors: horwitz ma. Vaccine. 2016 Sep 22;34(41):4969-4978. doi: 10.1016/j.vaccine.2016.08.041. Epub 2016 Aug 28. Vaccine. 2016. PMID: 27577555 Free PMC article.
A Francisella tularensis live vaccine strain (LVS) mutant with a deletion in capB, encoding a putative capsular biosynthesis protein, is significantly more attenuated than LVS yet induces potent protective immunity in mice against F. tularensis challenge.
Jia Q, Lee BY, Bowen R, Dillon BJ, Som SM, Horwitz MA. Jia Q, et al. Among authors: horwitz ma. Infect Immun. 2010 Oct;78(10):4341-55. doi: 10.1128/IAI.00192-10. Epub 2010 Jul 19. Infect Immun. 2010. PMID: 20643859 Free PMC article.
181 results