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Cell subtype-specific effects of genetic variation in the Alzheimer's disease brain.
Fujita M, Gao Z, Zeng L, McCabe C, White CC, Ng B, Green GS, Rozenblatt-Rosen O, Phillips D, Amir-Zilberstein L, Lee H, Pearse RV 2nd, Khan A, Vardarajan BN, Kiryluk K, Ye CJ, Klein HU, Wang G, Regev A, Habib N, Schneider JA, Wang Y, Young-Pearse T, Mostafavi S, Bennett DA, Menon V, De Jager PL. Fujita M, et al. Among authors: mccabe c. Nat Genet. 2024 Apr;56(4):605-614. doi: 10.1038/s41588-024-01685-y. Epub 2024 Mar 21. Nat Genet. 2024. PMID: 38514782
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer's disease.
Mostafavi S, Gaiteri C, Sullivan SE, White CC, Tasaki S, Xu J, Taga M, Klein HU, Patrick E, Komashko V, McCabe C, Smith R, Bradshaw EM, Root DE, Regev A, Yu L, Chibnik LB, Schneider JA, Young-Pearse TL, Bennett DA, De Jager PL. Mostafavi S, et al. Among authors: mccabe c. Nat Neurosci. 2018 Jun;21(6):811-819. doi: 10.1038/s41593-018-0154-9. Epub 2018 May 25. Nat Neurosci. 2018. PMID: 29802388 Free PMC article.
Multicellular communities are perturbed in the aging human brain and Alzheimer's disease.
Cain A, Taga M, McCabe C, Green GS, Hekselman I, White CC, Lee DI, Gaur P, Rozenblatt-Rosen O, Zhang F, Yeger-Lotem E, Bennett DA, Yang HS, Regev A, Menon V, Habib N, De Jager PL. Cain A, et al. Among authors: mccabe c. Nat Neurosci. 2023 Jul;26(7):1267-1280. doi: 10.1038/s41593-023-01356-x. Epub 2023 Jun 19. Nat Neurosci. 2023. PMID: 37336975 Free PMC article.
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C, Tang A, Raj T, Replogle J, Brodeur W, Gabriel S, Chai HS, Younkin C, Younkin SG, Zou F, Szyf M, Epstein CB, Schneider JA, Bernstein BE, Meissner A, Ertekin-Taner N, Chibnik LB, Kellis M, Mill J, Bennett DA. De Jager PL, et al. Among authors: mccabe c. Nat Neurosci. 2014 Sep;17(9):1156-63. doi: 10.1038/nn.3786. Epub 2014 Aug 17. Nat Neurosci. 2014. PMID: 25129075 Free PMC article.
A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research.
De Jager PL, Ma Y, McCabe C, Xu J, Vardarajan BN, Felsky D, Klein HU, White CC, Peters MA, Lodgson B, Nejad P, Tang A, Mangravite LM, Yu L, Gaiteri C, Mostafavi S, Schneider JA, Bennett DA. De Jager PL, et al. Among authors: mccabe c. Sci Data. 2018 Aug 7;5:180142. doi: 10.1038/sdata.2018.142. Sci Data. 2018. PMID: 30084846 Free PMC article.
Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains.
Klein HU, McCabe C, Gjoneska E, Sullivan SE, Kaskow BJ, Tang A, Smith RV, Xu J, Pfenning AR, Bernstein BE, Meissner A, Schneider JA, Mostafavi S, Tsai LH, Young-Pearse TL, Bennett DA, De Jager PL. Klein HU, et al. Among authors: mccabe c. Nat Neurosci. 2019 Jan;22(1):37-46. doi: 10.1038/s41593-018-0291-1. Epub 2018 Dec 17. Nat Neurosci. 2019. PMID: 30559478 Free PMC article.
Nuclei multiplexing with barcoded antibodies for single-nucleus genomics.
Gaublomme JT, Li B, McCabe C, Knecht A, Yang Y, Drokhlyansky E, Van Wittenberghe N, Waldman J, Dionne D, Nguyen L, De Jager PL, Yeung B, Zhao X, Habib N, Rozenblatt-Rosen O, Regev A. Gaublomme JT, et al. Among authors: mccabe c. Nat Commun. 2019 Jul 2;10(1):2907. doi: 10.1038/s41467-019-10756-2. Nat Commun. 2019. PMID: 31266958 Free PMC article.
Disease-associated astrocytes in Alzheimer's disease and aging.
Habib N, McCabe C, Medina S, Varshavsky M, Kitsberg D, Dvir-Szternfeld R, Green G, Dionne D, Nguyen L, Marshall JL, Chen F, Zhang F, Kaplan T, Regev A, Schwartz M. Habib N, et al. Among authors: mccabe c. Nat Neurosci. 2020 Jun;23(6):701-706. doi: 10.1038/s41593-020-0624-8. Epub 2020 Apr 27. Nat Neurosci. 2020. PMID: 32341542 Free PMC article.
1,242 results