Niemi M - Search Results

1

Non-targeted metabolomics for the identification of plasma metabolites associated with organic anion transporting polypeptide 1B1 function.

Hämäläinen K, Hirvensalo P, Neuvonen M, Tornio A, Backman JT, Lehtonen M, Niemi M. Hämäläinen K, et al. Among authors: niemi m. Clin Transl Sci. 2024 Mar;17(3):e13773. doi: 10.1111/cts.13773. Clin Transl Sci. 2024. PMID: 38515340 Free PMC article.

2

Pharmacogenomics of celiprolol - evidence for a role of P-glycoprotein and organic anion transporting polypeptide 1A2 in celiprolol pharmacokinetics.

Hirvensalo P, Tornio A, Tapaninen T, Paile-Hyvärinen M, Neuvonen M, Backman JT, Niemi M. Hirvensalo P, et al. Among authors: niemi m. Clin Transl Sci. 2022 Feb;15(2):409-421. doi: 10.1111/cts.13159. Epub 2021 Sep 29. Clin Transl Sci. 2022. PMID: 34585840 Free PMC article.

3

Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics.

Niemi M, Backman JT, Kajosaari LI, Leathart JB, Neuvonen M, Daly AK, Eichelbaum M, Kivistö KT, Neuvonen PJ. Niemi M, et al. Clin Pharmacol Ther. 2005 Jun;77(6):468-78. doi: 10.1016/j.clpt.2005.01.018. Clin Pharmacol Ther. 2005. PMID: 15961978

4

Frequencies of single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide 1B1 SLCO1B1 gene in a Finnish population.

Pasanen MK, Backman JT, Neuvonen PJ, Niemi M. Pasanen MK, et al. Among authors: niemi m. Eur J Clin Pharmacol. 2006 Jun;62(6):409-15. doi: 10.1007/s00228-006-0123-1. Epub 2006 Apr 21. Eur J Clin Pharmacol. 2006. PMID: 16758257

5

Gender, but not CYP7A1 or SLCO1B1 polymorphism, affects the fasting plasma concentrations of bile acids in human beings.

Xiang X, Backman JT, Neuvonen PJ, Niemi M. Xiang X, et al. Among authors: niemi m. Basic Clin Pharmacol Toxicol. 2012 Mar;110(3):245-52. doi: 10.1111/j.1742-7843.2011.00792.x. Epub 2011 Oct 7. Basic Clin Pharmacol Toxicol. 2012. PMID: 21902813 Free article.

6

SLCO1B1 polymorphism markedly affects the pharmacokinetics of lovastatin acid.

Tornio A, Vakkilainen J, Neuvonen M, Backman JT, Neuvonen PJ, Niemi M. Tornio A, et al. Among authors: niemi m. Pharmacogenet Genomics. 2015 Aug;25(8):382-7. doi: 10.1097/FPC.0000000000000148. Pharmacogenet Genomics. 2015. PMID: 26020121

7

Clopidogrel Has No Clinically Meaningful Effect on the Pharmacokinetics of the Organic Anion Transporting Polypeptide 1B1 and Cytochrome P450 3A4 Substrate Simvastatin.

Itkonen MK, Tornio A, Neuvonen M, Neuvonen PJ, Niemi M, Backman JT. Itkonen MK, et al. Among authors: niemi m. Drug Metab Dispos. 2015 Nov;43(11):1655-60. doi: 10.1124/dmd.115.065938. Epub 2015 Sep 1. Drug Metab Dispos. 2015. PMID: 26329790 Clinical Trial.

8

Role of gemfibrozil as an inhibitor of CYP2C8 and membrane transporters.

Tornio A, Neuvonen PJ, Niemi M, Backman JT. Tornio A, et al. Among authors: niemi m. Expert Opin Drug Metab Toxicol. 2017 Jan;13(1):83-95. doi: 10.1080/17425255.2016.1227791. Epub 2016 Aug 31. Expert Opin Drug Metab Toxicol. 2017. PMID: 27548563 Review.

9

Comprehensive Pharmacogenomic Study Reveals an Important Role of UGT1A3 in Montelukast Pharmacokinetics.

Hirvensalo P, Tornio A, Neuvonen M, Tapaninen T, Paile-Hyvärinen M, Kärjä V, Männistö VT, Pihlajamäki J, Backman JT, Niemi M. Hirvensalo P, et al. Among authors: niemi m. Clin Pharmacol Ther. 2018 Jul;104(1):158-168. doi: 10.1002/cpt.891. Epub 2017 Nov 6. Clin Pharmacol Ther. 2018. PMID: 28940478 Free PMC article.

10

Enantiospecific Pharmacogenomics of Fluvastatin.

Hirvensalo P, Tornio A, Neuvonen M, Kiander W, Kidron H, Paile-Hyvärinen M, Tapaninen T, Backman JT, Niemi M. Hirvensalo P, et al. Among authors: niemi m. Clin Pharmacol Ther. 2019 Sep;106(3):668-680. doi: 10.1002/cpt.1463. Epub 2019 May 14. Clin Pharmacol Ther. 2019. PMID: 30989645 Free PMC article.

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