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CCL21-DC in situ vaccination in murine NSCLC overcomes resistance to immunotherapy and generates systemic tumor-specific immunity.
Salehi-Rad R, Lim RJ, Du Y, Tran LM, Li R, Ong SL, Ling Huang Z, Dumitras C, Zhang T, Park SJ, Crosson W, Kahangi B, Abascal J, Seet C, Oh M, Shabihkhani M, Paul M, Krysan K, Lisberg AE, Garon EB, Liu B, Dubinett SM. Salehi-Rad R, et al. Among authors: krysan k. J Immunother Cancer. 2023 Sep;11(9):e006896. doi: 10.1136/jitc-2023-006896. J Immunother Cancer. 2023. PMID: 37730274 Free PMC article.
The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring.
Batool SM, Yekula A, Khanna P, Hsia T, Gamblin AS, Ekanayake E, Escobedo AK, You DG, Castro CM, Im H, Kilic T, Garlin MA, Skog J, Dinulescu DM, Dudley J, Agrawal N, Cheng J, Abtin F, Aberle DR, Chia D, Elashoff D, Grognan T, Krysan K, Oh SS, Strom C, Tu M, Wei F, Xian RR, Skates SJ, Zhang DY, Trinh T, Watson M, Aft R, Rawal S, Agarwal A, Kesmodel SB, Yang C, Shen C, Hochberg FH, Wong DTW, Patel AA, Papadopoulos N, Bettegowda C, Cote RJ, Srivastava S, Lee H, Carter BS, Balaj L. Batool SM, et al. Among authors: krysan k. Cell Rep Med. 2023 Oct 17;4(10):101198. doi: 10.1016/j.xcrm.2023.101198. Epub 2023 Sep 15. Cell Rep Med. 2023. PMID: 37716353 Free PMC article. Review.
Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma.
Yanagawa J, Tran LM, Salehi-Rad R, Lim RJ, Dumitras C, Fung E, Wallace WD, Prosper AE, Fishbein G, Shea C, Hong R, Kahangi B, Deng JJ, Gower AC, Liu B, Campbell JD, Mazzilli SA, Beane JE, Kadara H, Lenburg ME, Spira AE, Aberle DR, Krysan K, Dubinett SM. Yanagawa J, et al. Among authors: krysan k. Cancer Res. 2023 Oct 2;83(19):3305-3319. doi: 10.1158/0008-5472.CAN-23-0128. Cancer Res. 2023. PMID: 37477508 Free PMC article.
Comprehensive tissue deconvolution of cell-free DNA by deep learning for disease diagnosis and monitoring.
Li S, Zeng W, Ni X, Liu Q, Li W, Stackpole ML, Zhou Y, Gower A, Krysan K, Ahuja P, Lu DS, Raman SS, Hsu W, Aberle DR, Magyar CE, French SW, Han SB, Garon EB, Agopian VG, Wong WH, Dubinett SM, Zhou XJ. Li S, et al. Among authors: krysan k. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2305236120. doi: 10.1073/pnas.2305236120. Epub 2023 Jul 3. Proc Natl Acad Sci U S A. 2023. PMID: 37399400 Free PMC article.
Response and recurrence correlates in individuals treated with neoadjuvant anti-PD-1 therapy for resectable oral cavity squamous cell carcinoma.
Liu S, Knochelmann HM, Lomeli SH, Hong A, Richardson M, Yang Z, Lim RJ, Wang Y, Dumitras C, Krysan K, Timmers C, Romeo MJ, Krieg C, O'Quinn EC, Horton JD, Dubinett SM, Paulos CM, Neskey DM, Lo RS. Liu S, et al. Among authors: krysan k. Cell Rep Med. 2021 Oct 19;2(10):100411. doi: 10.1016/j.xcrm.2021.100411. eCollection 2021 Oct 19. Cell Rep Med. 2021. PMID: 34755131 Free PMC article. Clinical Trial.
Early Diagnosis and Screening for Lung Cancer.
Kadara H, Tran LM, Liu B, Vachani A, Li S, Sinjab A, Zhou XJ, Dubinett SM, Krysan K. Kadara H, et al. Among authors: krysan k. Cold Spring Harb Perspect Med. 2021 Sep 1;11(9):a037994. doi: 10.1101/cshperspect.a037994. Cold Spring Harb Perspect Med. 2021. PMID: 34001525 Free PMC article. Review.
Resolving the Spatial and Cellular Architecture of Lung Adenocarcinoma by Multiregion Single-Cell Sequencing.
Sinjab A, Han G, Treekitkarnmongkol W, Hara K, Brennan PM, Dang M, Hao D, Wang R, Dai E, Dejima H, Zhang J, Bogatenkova E, Sanchez-Espiridion B, Chang K, Little DR, Bazzi S, Tran LM, Krysan K, Behrens C, Duose DY, Parra ER, Raso MG, Solis LM, Fukuoka J, Zhang J, Sepesi B, Cascone T, Byers LA, Gibbons DL, Chen J, Moghaddam SJ, Ostrin EJ, Rosen D, Heymach JV, Scheet P, Dubinett SM, Fujimoto J, Wistuba II, Stevenson CS, Spira A, Wang L, Kadara H. Sinjab A, et al. Among authors: krysan k. Cancer Discov. 2021 Oct;11(10):2506-2523. doi: 10.1158/2159-8290.CD-20-1285. Epub 2021 May 10. Cancer Discov. 2021. PMID: 33972311 Free PMC article.
Inhibition of Granulocytic Myeloid-Derived Suppressor Cells Overcomes Resistance to Immune Checkpoint Inhibition in LKB1-Deficient Non-Small Cell Lung Cancer.
Li R, Salehi-Rad R, Crosson W, Momcilovic M, Lim RJ, Ong SL, Huang ZL, Zhang T, Abascal J, Dumitras C, Jing Z, Park SJ, Krysan K, Shackelford DB, Tran LM, Liu B, Dubinett SM. Li R, et al. Among authors: krysan k. Cancer Res. 2021 Jun 15;81(12):3295-3308. doi: 10.1158/0008-5472.CAN-20-3564. Epub 2021 Apr 14. Cancer Res. 2021. PMID: 33853830 Free PMC article.
Novel Kras-mutant murine models of non-small cell lung cancer possessing co-occurring oncogenic mutations and increased tumor mutational burden.
Salehi-Rad R, Li R, Tran LM, Lim RJ, Abascal J, Momcilovic M, Park SJ, Ong SL, Shabihkhani M, Huang ZL, Paul M, Shackelford DB, Krysan K, Liu B, Dubinett SM. Salehi-Rad R, et al. Among authors: krysan k. Cancer Immunol Immunother. 2021 Aug;70(8):2389-2400. doi: 10.1007/s00262-020-02837-9. Epub 2021 Jan 28. Cancer Immunol Immunother. 2021. PMID: 33507343 Free PMC article.
59 results