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Page 1
Study protocol for a Randomised controlled trial of EArly transjugular intrahepatiC porTosystemic stent-shunt in Acute Variceal Bleeding (REACT-AVB trial).
Tripathi D, Patch D, Mehrzad H, Yu D, Aspinall RJ, Armstrong MJ, Stanley A, Ireland H, Travis S, Hayes P, Lomax M, Roslund N, Lam E, Slinn G, Jowett S, Moakes C, Maher A, Brettell E, Sehmi S; REACT-AVB trial collaborative group. Tripathi D, et al. Among authors: brettell e. BMJ Open Gastroenterol. 2024 Mar 22;11(1):e001314. doi: 10.1136/bmjgast-2023-001314. BMJ Open Gastroenterol. 2024. PMID: 38519049 Free PMC article.
Withdrawal of renin-angiotensin system inhibitors’ effect on estimated glomerular filtration rate in adults with advanced kidney disease: the STOP-ACEi RCT.
Bhandari S, Mehta S, Khwaja A, Cleland J, Ives N, Brettell E, Chadburn M, Cockwell P; for the STOP-ACEi Trial Investigators. Bhandari S, et al. Among authors: brettell e. Southampton (UK): National Institute for Health and Care Research; 2024 Mar. Southampton (UK): National Institute for Health and Care Research; 2024 Mar. PMID: 38564538 Free Books & Documents. Review.
Protocol for a multicentre randomised controlled trial of STeroid Administration Routes For Idiopathic Sudden sensorineural Hearing loss: The STARFISH trial.
Smith ME, Knappett R, Vickers D, White D, Schramm CJ, Mehta S, Sun Y, Watkins B, Chadburn M, Jarrett H, James K, Brettell E, Roberts TE, Bance ML; INTEGRATE (the UK ENT Trainee Research Network); Tysome JR. Smith ME, et al. Among authors: brettell e. PLoS One. 2024 Feb 29;19(2):e0290480. doi: 10.1371/journal.pone.0290480. eCollection 2024. PLoS One. 2024. PMID: 38422002 Free PMC article.
Can we achieve better trial recruitment by presenting patient information through multimedia? Meta-analysis of 'studies within a trial' (SWATs).
Madurasinghe VW, Knapp P, Eldridge S, Collier D, Treweek S, Rick J, Graffy J, Parker A, Salisbury C, Torgerson D, Jolly K, Sidhu MS, Fife-Schaw C, Hull MA, Sprange K, Brettell E, Bhandari S, Montgomery A, Bower P. Madurasinghe VW, et al. Among authors: brettell e. BMC Med. 2023 Nov 8;21(1):425. doi: 10.1186/s12916-023-03081-5. BMC Med. 2023. PMID: 37940944 Free PMC article.
The Growth Hormone Deficiency (GHD) Reversal Trial: effect on final height of discontinuation versus continuation of growth hormone treatment in pubertal children with isolated GHD-a non-inferiority Randomised Controlled Trial (RCT).
Brettell E, Högler W, Woolley R, Cummins C, Mathers J, Oppong R, Roy L, Khan A, Hunt C, Dattani M; G. H. D. study group. Brettell E, et al. Trials. 2023 Aug 21;24(1):548. doi: 10.1186/s13063-023-07562-z. Trials. 2023. PMID: 37605233 Free PMC article. Clinical Trial.
Renin-Angiotensin System Inhibition in Advanced Chronic Kidney Disease.
Bhandari S, Mehta S, Khwaja A, Cleland JGF, Ives N, Brettell E, Chadburn M, Cockwell P; STOP ACEi Trial Investigators. Bhandari S, et al. Among authors: brettell e. N Engl J Med. 2022 Dec 1;387(22):2021-2032. doi: 10.1056/NEJMoa2210639. Epub 2022 Nov 3. N Engl J Med. 2022. PMID: 36326117 Free article. Clinical Trial.
Plasma exchange and glucocorticoids to delay death or end-stage renal disease in anti-neutrophil cytoplasm antibody-associated vasculitis: PEXIVAS non-inferiority factorial RCT.
Jayne D, Walsh M, Merkel PA, Peh CA, Szpirt W, Puéchal X, Fujimoto S, Hawley C, Khalidi N, Jones R, Flossmann O, Wald R, Girard L, Levin A, Gregorini G, Harper L, Clark W, Pagnoux C, Specks U, Smyth L, Ito-Ihara T, de Zoysa J, Brezina B, Mazzetti A, McAlear CA, Reidlinger D, Mehta S, Ives N, Brettell EA, Jarrett H, Wheatley K, Broadhurst E, Casian A, Pusey CD. Jayne D, et al. Among authors: brettell ea. Health Technol Assess. 2022 Sep;26(38):1-60. doi: 10.3310/PNXB5040. Health Technol Assess. 2022. PMID: 36155131 Free article. Clinical Trial.
Economic Evaluation of Using Daily Prednisolone versus Placebo at the Time of an Upper Respiratory Tract Infection for the Management of Children with Steroid-Sensitive Nephrotic Syndrome: A Model-Based Analysis.
Afentou N, Frew E, Mehta S, Ives NJ, Woolley RL, Brettell EA, Khan AR, Milford DV, Bockenhauer D, Saleem MA, Hall AS, Koziell A, Maxwell H, Hegde S, Finlay E, Gilbert RD, Jones C, McKeever K, Cook W, Webb NJA, Christian MT; PREDNOS Collaborative Group, NIHR Medicines for Children Research Network Nephrology Clinical Studies Group. Afentou N, et al. Among authors: brettell ea. Pharmacoecon Open. 2022 Jul;6(4):605-617. doi: 10.1007/s41669-022-00334-6. Epub 2022 Jun 22. Pharmacoecon Open. 2022. PMID: 35733076 Free PMC article.
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