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Discovery of HC-7366: An Orally Bioavailable and Efficacious GCN2 Kinase Activator.
Thomson CG, Aicher TD, Cheng W, Du H, Dudgeon C, Li AH, Li B, Lightcap E, Luo D, Mulvihill M, Pan P, Rahemtulla BF, Rigby AC, Sherborne B, Sood S, Surguladze D, Talbot EPA, Tameire F, Taylor S, Wang Y, Wojnarowicz P, Xiao F, Ramurthy S. Thomson CG, et al. Among authors: wang y. J Med Chem. 2024 Apr 11;67(7):5259-5271. doi: 10.1021/acs.jmedchem.3c02384. Epub 2024 Mar 26. J Med Chem. 2024. PMID: 38530741
Molecular Engineering of Efficacious Mono-Valent Ultra-Long Acting Two-Chain Insulin-Fc Conjugates.
Tagmose TM, Pedersen KM, Pridal L, Stidsen CE, Pedersen MØ, Lin Z, Zhang Y, Wan Z, Ferreras M, Naver H, Nielsen PK, Cao Z, Wang Y, Lykke L, Christensen JL, Jensen VS, Manfè V, Pedersen TÅ, Johansson E, Madsen P, Kodra JT, Münzel M, De Maria L, Nishimura E, Kjeldsen TB. Tagmose TM, et al. Among authors: wang y. J Med Chem. 2022 Feb 10;65(3):2633-2645. doi: 10.1021/acs.jmedchem.1c02039. Epub 2022 Feb 1. J Med Chem. 2022. PMID: 35104142
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