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Initial characterization of a transgenic mouse with overexpression of the human D1-dopamine receptor in the heart.
Abella LMR, Jacob H, Hesse C, Hofmann B, Schneider S, Schindler L, Keller M, Buchwalow IB, Jin C, Panula P, Dhein S, Klimas J, Hadova K, Gergs U, Neumann J. Abella LMR, et al. Among authors: klimas j. Naunyn Schmiedebergs Arch Pharmacol. 2024 Jan 4. doi: 10.1007/s00210-023-02901-y. Online ahead of print. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 38177456
Triadin is a critical determinant of cellular Ca cycling and contractility in the heart.
Kirchhefer U, Klimas J, Baba HA, Buchwalow IB, Fabritz L, Hüls M, Matus M, Müller FU, Schmitz W, Neumann J. Kirchhefer U, et al. Among authors: klimas j. Am J Physiol Heart Circ Physiol. 2007 Nov;293(5):H3165-74. doi: 10.1152/ajpheart.00799.2007. Epub 2007 Sep 21. Am J Physiol Heart Circ Physiol. 2007. PMID: 17890426 Free article.
Stress and high heart rate provoke ventricular tachycardia in mice expressing triadin.
Kirchhof P, Klimas J, Fabritz L, Zwiener M, Jones LR, Schäfers M, Hermann S, Boknik P, Schmitz W, Breithardt G, Kirchhefer U, Neumann J. Kirchhof P, et al. Among authors: klimas j. J Mol Cell Cardiol. 2007 May;42(5):962-71. doi: 10.1016/j.yjmcc.2007.02.012. Epub 2007 Mar 7. J Mol Cell Cardiol. 2007. PMID: 17408688
Rapid changes of mRNA expressions of cardiac ion channels affected by Torsadogenic drugs influence susceptibility of rat hearts to arrhythmias induced by Beta-Adrenergic stimulation.
Hadova K, Kmecova J, Ochodnicka-Mackovicova K, Kralova E, Doka G, Bies Pivackova L, Vavrinec P, Stankovicova T, Krenek P, Klimas J. Hadova K, et al. Among authors: klimas j. Pharmacol Res Perspect. 2023 Oct;11(5):e01134. doi: 10.1002/prp2.1134. Pharmacol Res Perspect. 2023. PMID: 37715323 Free PMC article.
151 results