Schindler L - Search Results

1

Initial Characterization of a Transgenic Mouse with Overexpression of the Human H₁-Histamine Receptor on the Heart.

Rayo Abella LM, Jacob H, Keller M, Schindler L, Pockes S, Pitzl S, Klimas J, Hadova K, Schneider S, Buchwalow IB, Jin C, Panula P, Kirchhefer U, Neumann J, Gergs U. Rayo Abella LM, et al. Among authors: schindler l. J Pharmacol Exp Ther. 2024 Apr 18;389(2):174-185. doi: 10.1124/jpet.123.002060. J Pharmacol Exp Ther. 2024. PMID: 38531640

2

Initial characterization of a transgenic mouse with overexpression of the human D₁-dopamine receptor in the heart.

Abella LMR, Jacob H, Hesse C, Hofmann B, Schneider S, Schindler L, Keller M, Buchwalow IB, Jin C, Panula P, Dhein S, Klimas J, Hadova K, Gergs U, Neumann J. Abella LMR, et al. Among authors: schindler l. Naunyn Schmiedebergs Arch Pharmacol. 2024 Jan 4. doi: 10.1007/s00210-023-02901-y. Online ahead of print. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 38177456

3

Modifications at Arg and Ile Give Neurotensin(8-13) Derivatives with High Stability and Retained NTS₁ Receptor Affinity.

Schindler L, Bernhardt G, Keller M. Schindler L, et al. ACS Med Chem Lett. 2019 May 10;10(6):960-965. doi: 10.1021/acsmedchemlett.9b00122. eCollection 2019 Jun 13. ACS Med Chem Lett. 2019. PMID: 31223455 Free PMC article.

4

Toward Labeled Argininamide-Type NPY Y1 Receptor Antagonists: Identification of a Favorable Propionylation Site in BIBO3304.

Keller M, Schindler L, Bernhardt G, Buschauer A. Keller M, et al. Among authors: schindler l. Arch Pharm (Weinheim). 2015 Jun;348(6):390-8. doi: 10.1002/ardp.201400427. Epub 2015 Apr 17. Arch Pharm (Weinheim). 2015. PMID: 25884646

5

An Alkyne-functionalized Arginine for Solid-Phase Synthesis Enabling "Bioorthogonal" Peptide Conjugation.

Spinnler K, von Krüchten L, Konieczny A, Schindler L, Bernhardt G, Keller M. Spinnler K, et al. Among authors: schindler l. ACS Med Chem Lett. 2019 Sep 30;11(3):334-339. doi: 10.1021/acsmedchemlett.9b00388. eCollection 2020 Mar 12. ACS Med Chem Lett. 2019. PMID: 32184966 Free PMC article.

6

Neurotensin analogs by fluoroglycosylation at N^ω-carbamoylated arginines for PET imaging of NTS1-positive tumors.

Schindler L, Wohlfahrt K, Gluhacevic von Krüchten L, Prante O, Keller M, Maschauer S. Schindler L, et al. Sci Rep. 2022 Sep 2;12(1):15028. doi: 10.1038/s41598-022-19296-0. Sci Rep. 2022. PMID: 36056076 Free PMC article.

7

Fluorescence Labeling of Neurotensin(8-13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity.

Keller M, Mahuroof SA, Hong Yee V, Carpenter J, Schindler L, Littmann T, Pegoli A, Hübner H, Bernhardt G, Gmeiner P, Holliday ND. Keller M, et al. Among authors: schindler l. ACS Med Chem Lett. 2019 Nov 19;11(1):16-22. doi: 10.1021/acsmedchemlett.9b00462. eCollection 2020 Jan 9. ACS Med Chem Lett. 2019. PMID: 31938457 Free PMC article.

8

Development of a Neurotensin-Derived ⁶⁸Ga-Labeled PET Ligand with High In Vivo Stability for Imaging of NTS₁ Receptor-Expressing Tumors.

Schindler L, Moosbauer J, Schmidt D, Spruss T, Grätz L, Lüdeke S, Hofheinz F, Meister S, Echtenacher B, Bernhardt G, Pietzsch J, Hellwig D, Keller M. Schindler L, et al. Cancers (Basel). 2022 Oct 8;14(19):4922. doi: 10.3390/cancers14194922. Cancers (Basel). 2022. PMID: 36230845 Free PMC article.

9

N(ω)-Carbamoylation of the Argininamide Moiety: An Avenue to Insurmountable NPY Y1 Receptor Antagonists and a Radiolabeled Selective High-Affinity Molecular Tool ([(3)H]UR-MK299) with Extended Residence Time.

Keller M, Weiss S, Hutzler C, Kuhn KK, Mollereau C, Dukorn S, Schindler L, Bernhardt G, König B, Buschauer A. Keller M, et al. Among authors: schindler l. J Med Chem. 2015 Nov 25;58(22):8834-49. doi: 10.1021/acs.jmedchem.5b00925. Epub 2015 Nov 4. J Med Chem. 2015. PMID: 26466164

10

Insertion of Nanoluc into the Extracellular Loops as a Complementary Method To Establish BRET-Based Binding Assays for GPCRs.

Grätz L, Müller C, Pegoli A, Schindler L, Bernhardt G, Littmann T. Grätz L, et al. Among authors: schindler l. ACS Pharmacol Transl Sci. 2022 Oct 31;5(11):1142-1155. doi: 10.1021/acsptsci.2c00162. eCollection 2022 Nov 11. ACS Pharmacol Transl Sci. 2022. PMID: 36407949 Free PMC article.

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