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Genetic and Phenotypic Features of Schizophrenia in the UK Biobank.
Legge SE, Pardiñas AF, Woolway G, Rees E, Cardno AG, Escott-Price V, Holmans P, Kirov G, Owen MJ, O'Donovan MC, Walters JTR. Legge SE, et al. Among authors: holmans p. JAMA Psychiatry. 2024 Mar 27:e240200. doi: 10.1001/jamapsychiatry.2024.0200. Online ahead of print. JAMA Psychiatry. 2024. PMID: 38536179 Free PMC article.
Association Between Schizophrenia-Related Polygenic Liability and the Occurrence and Level of Mood-Incongruent Psychotic Symptoms in Bipolar Disorder.
Allardyce J, Leonenko G, Hamshere M, Pardiñas AF, Forty L, Knott S, Gordon-Smith K, Porteous DJ, Haywood C, Di Florio A, Jones L, McIntosh AM, Owen MJ, Holmans P, Walters JTR, Craddock N, Jones I, O'Donovan MC, Escott-Price V. Allardyce J, et al. Among authors: holmans p. JAMA Psychiatry. 2018 Jan 1;75(1):28-35. doi: 10.1001/jamapsychiatry.2017.3485. JAMA Psychiatry. 2018. PMID: 29167880 Free PMC article.
A polygenic resilience score moderates the genetic risk for schizophrenia.
Hess JL, Tylee DS, Mattheisen M; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH); Børglum AD, Als TD, Grove J, Werge T, Mortensen PB, Mors O, Nordentoft M, Hougaard DM, Byberg-Grauholm J, Bækvad-Hansen M, Greenwood TA, Tsuang MT, Curtis D, Steinberg S, Sigurdsson E, Stefánsson H, Stefánsson K, Edenberg HJ, Holmans P, Faraone SV, Glatt SJ. Hess JL, et al. Among authors: holmans p. Mol Psychiatry. 2021 Mar;26(3):800-815. doi: 10.1038/s41380-019-0463-8. Epub 2019 Sep 6. Mol Psychiatry. 2021. PMID: 31492941 Free PMC article.
Association of Genetic Liability to Psychotic Experiences With Neuropsychotic Disorders and Traits.
Legge SE, Jones HJ, Kendall KM, Pardiñas AF, Menzies G, Bracher-Smith M, Escott-Price V, Rees E, Davis KAS, Hotopf M, Savage JE, Posthuma D, Holmans P, Kirov G, Owen MJ, O'Donovan MC, Zammit S, Walters JTR. Legge SE, et al. Among authors: holmans p. JAMA Psychiatry. 2019 Dec 1;76(12):1256-1265. doi: 10.1001/jamapsychiatry.2019.2508. JAMA Psychiatry. 2019. PMID: 31553412 Free PMC article.
Genetic association of FMRP targets with psychiatric disorders.
Clifton NE, Rees E, Holmans PA, Pardiñas AF, Harwood JC, Di Florio A, Kirov G, Walters JTR, O'Donovan MC, Owen MJ, Hall J, Pocklington AJ. Clifton NE, et al. Mol Psychiatry. 2021 Jul;26(7):2977-2990. doi: 10.1038/s41380-020-00912-2. Epub 2020 Oct 19. Mol Psychiatry. 2021. PMID: 33077856 Free PMC article.
Rare Copy Number Variants Are Associated With Poorer Cognition in Schizophrenia.
Hubbard L, Rees E, Morris DW, Lynham AJ, Richards AL, Pardiñas AF, Legge SE, Harold D, Zammit S, Corvin AC, Gill MG, Hall J, Holmans P, O'Donovan MC, Owen MJ, Donohoe G, Kirov G, Pocklington A, Walters JTR. Hubbard L, et al. Among authors: holmans p. Biol Psychiatry. 2021 Jul 1;90(1):28-34. doi: 10.1016/j.biopsych.2020.11.025. Epub 2020 Dec 19. Biol Psychiatry. 2021. PMID: 33678419
Associations Between Schizophrenia Polygenic Liability, Symptom Dimensions, and Cognitive Ability in Schizophrenia.
Legge SE, Cardno AG, Allardyce J, Dennison C, Hubbard L, Pardiñas AF, Richards A, Rees E, Di Florio A, Escott-Price V, Zammit S, Holmans P, Owen MJ, O'Donovan MC, Walters JTR. Legge SE, et al. Among authors: holmans p. JAMA Psychiatry. 2021 Oct 1;78(10):1143-1151. doi: 10.1001/jamapsychiatry.2021.1961. JAMA Psychiatry. 2021. PMID: 34347035 Free PMC article.
Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia.
Pardiñas AF, Smart SE, Willcocks IR, Holmans PA, Dennison CA, Lynham AJ, Legge SE, Baune BT, Bigdeli TB, Cairns MJ, Corvin A, Fanous AH, Frank J, Kelly B, McQuillin A, Melle I, Mortensen PB, Mowry BJ, Pato CN, Periyasamy S, Rietschel M, Rujescu D, Simonsen C, St Clair D, Tooney P, Wu JQ, Andreassen OA, Kowalec K, Sullivan PF, Murray RM, Owen MJ, MacCabe JH, O'Donovan MC, Walters JTR; Genetics Workstream of the Schizophrenia Treatment Resistance and Therapeutic Advances (STRATA) Consortium and the Schizophrenia Working Group of the Psychiatric Genomics Consortium (PGC); Ajnakina O, Alameda L, Barnes TRE, Berardi D, Bonora E, Camporesi S, Cleusix M, Conus P, Crespo-Facorro B, D'Andrea G, Demjaha A, Do KQ, Doody GA, Eap CB, Ferchiou A, Di Forti M, Guidi L, Homman L, Jenni R, Joyce EM, Kassoumeri L, Khadimallah I, Lastrina O, Muratori R, Noyan H, O'Neill FA, Pignon B, Restellini R, Richard JR, Schürhoff F, Španiel F, Szöke A, Tarricone I, Tortelli A, Üçok A, Vázquez-Bourgon J. Pardiñas AF, et al. Among authors: holmans pa. JAMA Psychiatry. 2022 Mar 1;79(3):260-269. doi: 10.1001/jamapsychiatry.2021.3799. JAMA Psychiatry. 2022. PMID: 35019943 Free PMC article.
440 results