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Genetic and Phenotypic Features of Schizophrenia in the UK Biobank.
Legge SE, Pardiñas AF, Woolway G, Rees E, Cardno AG, Escott-Price V, Holmans P, Kirov G, Owen MJ, O'Donovan MC, Walters JTR. Legge SE, et al. Among authors: owen mj. JAMA Psychiatry. 2024 Mar 27:e240200. doi: 10.1001/jamapsychiatry.2024.0200. Online ahead of print. JAMA Psychiatry. 2024. PMID: 38536179 Free PMC article.
Specificity of polygenic signatures across symptom dimensions in bipolar disorder: an analysis of UK Bipolar Disorder Research Network data.
Allardyce J, Cardno AG, Gordon-Smith K, Jones L, Di Florio A, Walters JTR, Holmans PA, Craddock NJ, Jones I, Owen MJ, Escott-Price V, O'Donovan MC. Allardyce J, et al. Among authors: owen mj. Lancet Psychiatry. 2023 Aug;10(8):623-631. doi: 10.1016/S2215-0366(23)00186-4. Epub 2023 Jul 9. Lancet Psychiatry. 2023. PMID: 37437579 Free article.
The molecular genetics of schizophrenia.
O'Donovan MC, Owen MJ. O'Donovan MC, et al. Among authors: owen mj. Ann Med. 1996 Dec;28(6):541-6. doi: 10.3109/07853899608999118. Ann Med. 1996. PMID: 9017113 Review.
CAG repeat length in the hKCa3 gene and symptom dimensions in schizophrenia.
Cardno AG, Bowen T, Guy CA, Jones LA, McCarthy G, Williams NM, Murphy KC, Spurlock G, Gray M, Sanders RD, Craddock N, McGuffin P, Owen MJ, O'Donovan MC. Cardno AG, et al. Among authors: owen mj. Biol Psychiatry. 1999 Jun 15;45(12):1592-6. doi: 10.1016/s0006-3223(99)00033-5. Biol Psychiatry. 1999. PMID: 10376120
Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk.
Moskvina V, Craddock N, Holmans P, Nikolov I, Pahwa JS, Green E; Wellcome Trust Case Control Consortium; Owen MJ, O'Donovan MC. Moskvina V, et al. Among authors: owen mj. Mol Psychiatry. 2009 Mar;14(3):252-60. doi: 10.1038/mp.2008.133. Epub 2008 Dec 9. Mol Psychiatry. 2009. PMID: 19065143 Free PMC article.
The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia.
Green EK, Grozeva D, Jones I, Jones L, Kirov G, Caesar S, Gordon-Smith K, Fraser C, Forty L, Russell E, Hamshere ML, Moskvina V, Nikolov I, Farmer A, McGuffin P; Wellcome Trust Case Control Consortium; Holmans PA, Owen MJ, O'Donovan MC, Craddock N. Green EK, et al. Among authors: owen mj. Mol Psychiatry. 2010 Oct;15(10):1016-22. doi: 10.1038/mp.2009.49. Epub 2009 Jul 21. Mol Psychiatry. 2010. PMID: 19621016 Free PMC article.
Evidence for rare and common genetic risk variants for schizophrenia at protein kinase C, alpha.
Carroll LS, Williams NM, Moskvina V, Russell E, Norton N, Williams HJ, Peirce T, Georgieva L, Dwyer S, Grozeva D, Greene E, Farmer A, McGuffin P, Morris DW, Corvin A, Gill M, Rujescu D, Sham P, Holmans P, Jones I, Kirov G, Craddock N, O'Donovan MC, Owen MJ. Carroll LS, et al. Among authors: owen mj. Mol Psychiatry. 2010 Nov;15(11):1101-11. doi: 10.1038/mp.2009.96. Epub 2009 Sep 29. Mol Psychiatry. 2010. PMID: 19786960
Recent genomic advances in schizophrenia.
Doherty JL, O'Donovan MC, Owen MJ. Doherty JL, et al. Among authors: owen mj. Clin Genet. 2012 Feb;81(2):103-9. doi: 10.1111/j.1399-0004.2011.01773.x. Epub 2011 Oct 5. Clin Genet. 2012. PMID: 21895634 Review.
De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia.
Kirov G, Pocklington AJ, Holmans P, Ivanov D, Ikeda M, Ruderfer D, Moran J, Chambert K, Toncheva D, Georgieva L, Grozeva D, Fjodorova M, Wollerton R, Rees E, Nikolov I, van de Lagemaat LN, Bayés A, Fernandez E, Olason PI, Böttcher Y, Komiyama NH, Collins MO, Choudhary J, Stefansson K, Stefansson H, Grant SG, Purcell S, Sklar P, O'Donovan MC, Owen MJ. Kirov G, et al. Among authors: owen mj. Mol Psychiatry. 2012 Feb;17(2):142-53. doi: 10.1038/mp.2011.154. Epub 2011 Nov 15. Mol Psychiatry. 2012. PMID: 22083728 Free PMC article.
1,096 results