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Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer.
Cortesi A, Gandolfi F, Arco F, Di Chiaro P, Valli E, Polletti S, Noberini R, Gualdrini F, Attanasio S, Citron F, Ho IL, Shah R, Yen EY, Spinella MC, Ronzoni S, Rodighiero S, Mitro N, Bonaldi T, Ghisletti S, Monticelli S, Viale A, Diaferia GR, Natoli G. Cortesi A, et al. Among authors: diaferia gr. Sci Adv. 2024 Mar 29;10(13):eadk5386. doi: 10.1126/sciadv.adk5386. Epub 2024 Mar 27. Sci Adv. 2024. PMID: 38536927 Free PMC article.
Zc3h10 is a novel mitochondrial regulator.
Audano M, Pedretti S, Cermenati G, Brioschi E, Diaferia GR, Ghisletti S, Cuomo A, Bonaldi T, Salerno F, Mora M, Grigore L, Garlaschelli K, Baragetti A, Bonacina F, Catapano AL, Norata GD, Crestani M, Caruso D, Saez E, De Fabiani E, Mitro N. Audano M, et al. Among authors: diaferia gr. EMBO Rep. 2018 Apr;19(4):e45531. doi: 10.15252/embr.201745531. Epub 2018 Mar 5. EMBO Rep. 2018. PMID: 29507079 Free PMC article.
A first exon termination checkpoint preferentially suppresses extragenic transcription.
Austenaa LMI, Piccolo V, Russo M, Prosperini E, Polletti S, Polizzese D, Ghisletti S, Barozzi I, Diaferia GR, Natoli G. Austenaa LMI, et al. Among authors: diaferia gr. Nat Struct Mol Biol. 2021 Apr;28(4):337-346. doi: 10.1038/s41594-021-00572-y. Epub 2021 Mar 25. Nat Struct Mol Biol. 2021. PMID: 33767452 Free PMC article.
36 results