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Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer.
Cortesi A, Gandolfi F, Arco F, Di Chiaro P, Valli E, Polletti S, Noberini R, Gualdrini F, Attanasio S, Citron F, Ho IL, Shah R, Yen EY, Spinella MC, Ronzoni S, Rodighiero S, Mitro N, Bonaldi T, Ghisletti S, Monticelli S, Viale A, Diaferia GR, Natoli G. Cortesi A, et al. Among authors: ghisletti s. Sci Adv. 2024 Mar 29;10(13):eadk5386. doi: 10.1126/sciadv.adk5386. Epub 2024 Mar 27. Sci Adv. 2024. PMID: 38536927 Free PMC article.
Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide.
Russo M, Gualdrini F, Vallelonga V, Prosperini E, Noberini R, Pedretti S, Borriero C, Di Chiaro P, Polletti S, Imperato G, Marenda M, Ghirardi C, Bedin F, Cuomo A, Rodighiero S, Bonaldi T, Mitro N, Ghisletti S, Natoli G. Russo M, et al. Among authors: ghisletti s. Mol Cell. 2024 Mar 7;84(5):967-980.e10. doi: 10.1016/j.molcel.2023.12.033. Epub 2024 Jan 18. Mol Cell. 2024. PMID: 38242130
The genomic landscapes of inflammation.
Natoli G, Ghisletti S, Barozzi I. Natoli G, et al. Among authors: ghisletti s. Genes Dev. 2011 Jan 15;25(2):101-6. doi: 10.1101/gad.2018811. Genes Dev. 2011. PMID: 21245163 Free PMC article. Review.
Deciphering cis-regulatory control in inflammatory cells.
Ghisletti S, Natoli G. Ghisletti S, et al. Philos Trans R Soc Lond B Biol Sci. 2013 May 6;368(1620):20120370. doi: 10.1098/rstb.2012.0370. Print 2013. Philos Trans R Soc Lond B Biol Sci. 2013. PMID: 23650641 Free PMC article. Review.
High constitutive activity of a broad panel of housekeeping and tissue-specific cis-regulatory elements depends on a subset of ETS proteins.
Curina A, Termanini A, Barozzi I, Prosperini E, Simonatto M, Polletti S, Silvola A, Soldi M, Austenaa L, Bonaldi T, Ghisletti S, Natoli G. Curina A, et al. Among authors: ghisletti s. Genes Dev. 2017 Feb 15;31(4):399-412. doi: 10.1101/gad.293134.116. Epub 2017 Mar 8. Genes Dev. 2017. PMID: 28275002 Free PMC article.
Latent enhancers activated by stimulation in differentiated cells.
Ostuni R, Piccolo V, Barozzi I, Polletti S, Termanini A, Bonifacio S, Curina A, Prosperini E, Ghisletti S, Natoli G. Ostuni R, et al. Among authors: ghisletti s. Cell. 2013 Jan 17;152(1-2):157-71. doi: 10.1016/j.cell.2012.12.018. Cell. 2013. PMID: 23332752 Free article.
39 results