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Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer.
Cortesi A, Gandolfi F, Arco F, Di Chiaro P, Valli E, Polletti S, Noberini R, Gualdrini F, Attanasio S, Citron F, Ho IL, Shah R, Yen EY, Spinella MC, Ronzoni S, Rodighiero S, Mitro N, Bonaldi T, Ghisletti S, Monticelli S, Viale A, Diaferia GR, Natoli G. Cortesi A, et al. Among authors: polletti s. Sci Adv. 2024 Mar 29;10(13):eadk5386. doi: 10.1126/sciadv.adk5386. Epub 2024 Mar 27. Sci Adv. 2024. PMID: 38536927 Free PMC article.
Antioxidant metabolism regulates CD8+ T memory stem cell formation and antitumor immunity.
Pilipow K, Scamardella E, Puccio S, Gautam S, De Paoli F, Mazza EM, De Simone G, Polletti S, Buccilli M, Zanon V, Di Lucia P, Iannacone M, Gattinoni L, Lugli E. Pilipow K, et al. Among authors: polletti s. JCI Insight. 2018 Sep 20;3(18):e122299. doi: 10.1172/jci.insight.122299. eCollection 2018 Sep 20. JCI Insight. 2018. PMID: 30232291 Free PMC article.
Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans.
Galletti G, De Simone G, Mazza EMC, Puccio S, Mezzanotte C, Bi TM, Davydov AN, Metsger M, Scamardella E, Alvisi G, De Paoli F, Zanon V, Scarpa A, Camisa B, Colombo FS, Anselmo A, Peano C, Polletti S, Mavilio D, Gattinoni L, Boi SK, Youngblood BA, Jones RE, Baird DM, Gostick E, Llewellyn-Lacey S, Ladell K, Price DA, Chudakov DM, Newell EW, Casucci M, Lugli E. Galletti G, et al. Among authors: polletti s. Nat Immunol. 2020 Dec;21(12):1552-1562. doi: 10.1038/s41590-020-0791-5. Epub 2020 Oct 12. Nat Immunol. 2020. PMID: 33046887 Free PMC article.
Latent enhancers activated by stimulation in differentiated cells.
Ostuni R, Piccolo V, Barozzi I, Polletti S, Termanini A, Bonifacio S, Curina A, Prosperini E, Ghisletti S, Natoli G. Ostuni R, et al. Among authors: polletti s. Cell. 2013 Jan 17;152(1-2):157-71. doi: 10.1016/j.cell.2012.12.018. Cell. 2013. PMID: 23332752 Free article.
Dnmt3a restrains mast cell inflammatory responses.
Leoni C, Montagner S, Rinaldi A, Bertoni F, Polletti S, Balestrieri C, Monticelli S. Leoni C, et al. Among authors: polletti s. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1490-E1499. doi: 10.1073/pnas.1616420114. Epub 2017 Feb 6. Proc Natl Acad Sci U S A. 2017. PMID: 28167789 Free PMC article.
High constitutive activity of a broad panel of housekeeping and tissue-specific cis-regulatory elements depends on a subset of ETS proteins.
Curina A, Termanini A, Barozzi I, Prosperini E, Simonatto M, Polletti S, Silvola A, Soldi M, Austenaa L, Bonaldi T, Ghisletti S, Natoli G. Curina A, et al. Among authors: polletti s. Genes Dev. 2017 Feb 15;31(4):399-412. doi: 10.1101/gad.293134.116. Epub 2017 Mar 8. Genes Dev. 2017. PMID: 28275002 Free PMC article.
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