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A phase I study of the anaplastic lymphoma kinase inhibitor ceritinib in combination with gemcitabine-based chemotherapy in patients with advanced solid tumors.
Fountzilas C, Adjei A, Opyrchal M, Evans R, Ghasemi M, Attwood K, Groman A, Bshara W, Goey A, Wilton J, Ma WW, Iyer R. Fountzilas C, et al. Among authors: opyrchal m. Int J Cancer. 2021 Dec 15;149(12):2063-2074. doi: 10.1002/ijc.33754. Epub 2021 Aug 27. Int J Cancer. 2021. PMID: 34319586 Free PMC article. Clinical Trial.
Targeting PIM2 by JP11646 results in significant antitumor effects in solid tumors.
Katsuta E, Gil-Moore M, Moore J, Yousif M, Adjei AA, Ding Y, Caserta J, Baldino CM, Lee KP, Gelman IH, Takabe K, Opyrchal M. Katsuta E, et al. Among authors: opyrchal m. Int J Oncol. 2022 Oct;61(4):114. doi: 10.3892/ijo.2022.5404. Epub 2022 Aug 3. Int J Oncol. 2022. PMID: 35920189 Free PMC article.
A dose regimen-finding study to evaluate the safety, tolerability, pharmacokinetics, and activity of oratecan in subjects with advanced malignancies.
Boland PM, Fountzilas C, Fakih M, Opyrchal M, Diamond JR, Corr B, Ma WW, Redman M, Chan WK, Wang H, Kramer D, Kwan R, Cutler D, Zhi J, Jimeno A. Boland PM, et al. Among authors: opyrchal m. Cancer Chemother Pharmacol. 2022 Aug;90(2):175-187. doi: 10.1007/s00280-022-04453-z. Epub 2022 Jul 29. Cancer Chemother Pharmacol. 2022. PMID: 35904620 Clinical Trial.
68 results