Krahn JM - Search Results

1

Heparan sulfate selectively inhibits the collagenase activity of cathepsin K.

Zhang X, Luo Y, Hao H, Krahn JM, Su G, Dutcher R, Xu Y, Liu J, Pedersen LC, Xu D. Zhang X, et al. Among authors: krahn jm. Matrix Biol. 2024 May;129:15-28. doi: 10.1016/j.matbio.2024.03.005. Epub 2024 Mar 26. Matrix Biol. 2024. PMID: 38548090

2

Molecular mechanism of substrate specificity for heparan sulfate 2-O-sulfotransferase.

Liu C, Sheng J, Krahn JM, Perera L, Xu Y, Hsieh PH, Dou W, Liu J, Pedersen LC. Liu C, et al. Among authors: krahn jm. J Biol Chem. 2014 May 9;289(19):13407-18. doi: 10.1074/jbc.M113.530535. Epub 2014 Mar 20. J Biol Chem. 2014. PMID: 24652287 Free PMC article.

3

Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases.

Xu Y, Moon AF, Xu S, Krahn JM, Liu J, Pedersen LC. Xu Y, et al. Among authors: krahn jm. ACS Chem Biol. 2017 Jan 20;12(1):73-82. doi: 10.1021/acschembio.6b00841. Epub 2016 Nov 22. ACS Chem Biol. 2017. PMID: 28103688 Free PMC article.

4

Deciphering the substrate recognition mechanisms of the heparan sulfate 3-O-sulfotransferase-3.

Wander R, Kaminski AM, Xu Y, Pagadala V, Krahn JM, Pham TQ, Liu J, Pedersen LC. Wander R, et al. Among authors: krahn jm. RSC Chem Biol. 2021 May 28;2(4):1239-1248. doi: 10.1039/d1cb00079a. eCollection 2021 Aug 5. RSC Chem Biol. 2021. PMID: 34458837 Free PMC article.

5

Structural and substrate specificity analysis of 3-O-sulfotransferase isoform 5 to synthesize heparan sulfate.

Wander R, Kaminski AM, Wang Z, Stancanelli E, Xu Y, Pagadala V, Li J, Krahn JM, Pham TQ, Liu J, Pedersen LC. Wander R, et al. Among authors: krahn jm. ACS Catal. 2021 Dec 17;11(24):14956-14966. doi: 10.1021/acscatal.1c04520. Epub 2021 Nov 30. ACS Catal. 2021. PMID: 35223137 Free PMC article.

6

Probing Dominant Negative Behavior of Glucocorticoid Receptor β through a Hybrid Structural and Biochemical Approach.

Min J, Perera L, Krahn JM, Jewell CM, Moon AF, Cidlowski JA, Pedersen LC. Min J, et al. Among authors: krahn jm. Mol Cell Biol. 2018 Mar 29;38(8):e00453-17. doi: 10.1128/MCB.00453-17. Print 2018 Apr 15. Mol Cell Biol. 2018. PMID: 29437838 Free PMC article.

7

Structural characterization of the virulence factor Sda1 nuclease from Streptococcus pyogenes.

Moon AF, Krahn JM, Lu X, Cuneo MJ, Pedersen LC. Moon AF, et al. Among authors: krahn jm. Nucleic Acids Res. 2016 May 5;44(8):3946-57. doi: 10.1093/nar/gkw143. Epub 2016 Mar 11. Nucleic Acids Res. 2016. PMID: 26969731 Free PMC article.

8

A Structural Basis for Biguanide Activity.

Gabel SA, Duff MR, Pedersen LC, DeRose EF, Krahn JM, Howell EE, London RE. Gabel SA, et al. Among authors: krahn jm. Biochemistry. 2017 Sep 12;56(36):4786-4798. doi: 10.1021/acs.biochem.7b00619. Epub 2017 Aug 29. Biochemistry. 2017. PMID: 28766937 Free PMC article.

9

Targeting the Structural Maturation Pathway of HIV-1 Reverse Transcriptase.

Kirby TW, Gabel SA, DeRose EF, Perera L, Krahn JM, Pedersen LC, London RE. Kirby TW, et al. Among authors: krahn jm. Biomolecules. 2023 Nov 1;13(11):1603. doi: 10.3390/biom13111603. Biomolecules. 2023. PMID: 38002285 Free PMC article.

10

The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase.

Duff MR Jr, Gabel SA, Pedersen LC, DeRose EF, Krahn JM, Howell EE, London RE. Duff MR Jr, et al. Among authors: krahn jm. J Med Chem. 2020 Aug 13;63(15):8314-8324. doi: 10.1021/acs.jmedchem.0c00546. Epub 2020 Jul 28. J Med Chem. 2020. PMID: 32658475 Free PMC article.

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