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The oncolytic adenovirus Delta-24-RGD in combination with ONC201 induces a potent antitumor response in pediatric high-grade and diffuse midline glioma models.
de la Nava D, Ausejo-Mauleon I, Laspidea V, Gonzalez-Huarriz M, Lacalle A, Casares N, Zalacain M, Marrodan L, García-Moure M, Ochoa MC, Tallon-Cobos AC, Hernandez-Osuna R, Marco-Sanz J, Dhandapani L, Hervás-Corpión I, Becher OJ, Nazarian J, Mueller S, Phoenix TN, van der Lugt J, Hernaez M, Guruceaga E, Koschmann C, Venneti S, Allen JE, Dun MD, Fueyo J, Gomez-Manzano C, Gállego Pérez-Larraya J, Patiño-García A, Labiano S, Alonso MM. de la Nava D, et al. Among authors: guruceaga e. Neuro Oncol. 2024 Mar 30:noae066. doi: 10.1093/neuonc/noae066. Online ahead of print. Neuro Oncol. 2024. PMID: 38554031
Involvement of miRNAs in the differentiation of human glioblastoma multiforme stem-like cells.
Aldaz B, Sagardoy A, Nogueira L, Guruceaga E, Grande L, Huse JT, Aznar MA, Díez-Valle R, Tejada-Solís S, Alonso MM, Fernandez-Luna JL, Martinez-Climent JA, Malumbres R. Aldaz B, et al. Among authors: guruceaga e. PLoS One. 2013 Oct 14;8(10):e77098. doi: 10.1371/journal.pone.0077098. eCollection 2013. PLoS One. 2013. PMID: 24155920 Free PMC article.
A small noncoding RNA signature found in exosomes of GBM patient serum as a diagnostic tool.
Manterola L, Guruceaga E, Gállego Pérez-Larraya J, González-Huarriz M, Jauregui P, Tejada S, Diez-Valle R, Segura V, Samprón N, Barrena C, Ruiz I, Agirre A, Ayuso A, Rodríguez J, González A, Xipell E, Matheu A, López de Munain A, Tuñón T, Zazpe I, García-Foncillas J, Paris S, Delattre JY, Alonso MM. Manterola L, et al. Among authors: guruceaga e. Neuro Oncol. 2014 Apr;16(4):520-7. doi: 10.1093/neuonc/not218. Epub 2014 Jan 16. Neuro Oncol. 2014. PMID: 24435880 Free PMC article.
Analysis of SOX2-Regulated Transcriptome in Glioma Stem Cells.
Acanda de la Rocha AM, López-Bertoni H, Guruceaga E, González-Huarriz M, Martínez-Vélez N, Xipell E, Fueyo J, Gomez-Manzano C, Alonso MM. Acanda de la Rocha AM, et al. Among authors: guruceaga e. PLoS One. 2016 Sep 26;11(9):e0163155. doi: 10.1371/journal.pone.0163155. eCollection 2016. PLoS One. 2016. PMID: 27669421 Free PMC article.
miR-425-5p, a SOX2 target, regulates the expression of FOXJ3 and RAB31 and promotes the survival of GSCs.
de la Rocha AMA, González-Huarriz M, Guruceaga E, Mihelson N, Tejada-Solís S, Díez-Valle R, Martínez-Vélez N, Fueyo J, Gomez-Manzano C, Alonso MM, Laterra J, López-Bertoni H. de la Rocha AMA, et al. Among authors: guruceaga e. Arch Clin Biomed Res. 2020;4(3):221-238. doi: 10.26502/acbr.50170100. Epub 2020 Jun 18. Arch Clin Biomed Res. 2020. PMID: 32905473 Free PMC article.
Delta-24-RGD, an Oncolytic Adenovirus, Increases Survival and Promotes Proinflammatory Immune Landscape Remodeling in Models of AT/RT and CNS-PNET.
Garcia-Moure M, Gonzalez-Huarriz M, Labiano S, Guruceaga E, Bandres E, Zalacain M, Marrodan L, de Andrea C, Villalba M, Martinez-Velez N, Laspidea V, Puigdelloses M, Gallego Perez-Larraya J, Iñigo-Marco I, Stripecke R, Chan JA, Raabe EH, Kool M, Gomez-Manzano C, Fueyo J, Patiño-García A, Alonso MM. Garcia-Moure M, et al. Among authors: guruceaga e. Clin Cancer Res. 2021 Mar 15;27(6):1807-1820. doi: 10.1158/1078-0432.CCR-20-3313. Epub 2020 Dec 29. Clin Cancer Res. 2021. PMID: 33376098
Erratum: miR-425-5p, a SOX2 target, regulates the expression of FOXJ3 and RAB31 and promotes the survival of GSCs.
de la Rocha AMA, González-Huarriz M, Guruceaga E, Mihelson N, Tejada-Solís S, Díez-Valle R, Martínez-Vélez N, Fueyo J, Gomez-Manzano C, Alonso MM, Laterra J, López-Bertoni H. de la Rocha AMA, et al. Among authors: guruceaga e. Arch Clin Biomed Res. 2021;5(3):425-426. doi: 10.26502/acbr.50170176. Epub 2021 Jun 15. Arch Clin Biomed Res. 2021. PMID: 34888488 Free PMC article.
TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory.
Ausejo-Mauleon I, Labiano S, de la Nava D, Laspidea V, Zalacain M, Marrodán L, García-Moure M, González-Huarriz M, Hervás-Corpión I, Dhandapani L, Vicent S, Collantes M, Peñuelas I, Becher OJ, Filbin MG, Jiang L, Labelle J, de Biagi-Junior CAO, Nazarian J, Laternser S, Phoenix TN, van der Lugt J, Kranendonk M, Hoogendijk R, Mueller S, De Andrea C, Anderson AC, Guruceaga E, Koschmann C, Yadav VN, Gállego Pérez-Larraya J, Patiño-García A, Pastor F, Alonso MM. Ausejo-Mauleon I, et al. Among authors: guruceaga e. Cancer Cell. 2023 Nov 13;41(11):1911-1926.e8. doi: 10.1016/j.ccell.2023.09.001. Epub 2023 Oct 5. Cancer Cell. 2023. PMID: 37802053 Free PMC article.
PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas.
Pascual M, Mena-Varas M, Robles EF, Garcia-Barchino MJ, Panizo C, Hervas-Stubbs S, Alignani D, Sagardoy A, Martinez-Ferrandis JI, Bunting KL, Meier S, Sagaert X, Bagnara D, Guruceaga E, Blanco O, Celay J, Martínez-Baztan A, Casares N, Lasarte JJ, MacCarthy T, Melnick A, Martinez-Climent JA, Roa S. Pascual M, et al. Among authors: guruceaga e. Blood. 2019 May 30;133(22):2401-2412. doi: 10.1182/blood.2018889931. Epub 2019 Apr 11. Blood. 2019. PMID: 30975638 Free PMC article.
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