Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

205 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung.
Dörner PJ, Anandakumar H, Röwekamp I, Fiocca Vernengo F, Millet Pascual-Leone B, Krzanowski M, Sellmaier J, Brüning U, Fritsche-Guenther R, Pfannkuch L, Kurth F, Milek M, Igbokwe V, Löber U, Gutbier B, Holstein M, Heinz GA, Mashreghi MF, Schulte LN, Klatt AB, Caesar S, Wienhold SM, Offermanns S, Mack M, Witzenrath M, Jordan S, Beule D, Kirwan JA, Forslund SK, Wilck N, Bartolomaeus H, Heimesaat MM, Opitz B. Dörner PJ, et al. Among authors: opitz b. Nat Commun. 2024 Mar 30;15(1):2788. doi: 10.1038/s41467-024-47149-z. Nat Commun. 2024. PMID: 38555356 Free PMC article.
Streptococcus pneumoniae induced p38 MAPK- and NF-kappaB-dependent COX-2 expression in human lung epithelium.
N'Guessan PD, Hippenstiel S, Etouem MO, Zahlten J, Beermann W, Lindner D, Opitz B, Witzenrath M, Rosseau S, Suttorp N, Schmeck B. N'Guessan PD, et al. Among authors: opitz b. Am J Physiol Lung Cell Mol Physiol. 2006 Jun;290(6):L1131-8. doi: 10.1152/ajplung.00383.2005. Epub 2006 Jan 13. Am J Physiol Lung Cell Mol Physiol. 2006. PMID: 16414978 Free article.
[New aspects of the pathophysiology of pneumonia].
Hippenstiel S, Witzenrath M, Opitz B, Schütte H, Rosseau S, Suttorp N. Hippenstiel S, et al. Among authors: opitz b. Internist (Berl). 2007 May;48(5):459-60, 462-4, 466-7. doi: 10.1007/s00108-007-1837-6. Internist (Berl). 2007. PMID: 17429589 Free PMC article. Review. German.
The NLRP3 inflammasome is differentially activated by pneumolysin variants and contributes to host defense in pneumococcal pneumonia.
Witzenrath M, Pache F, Lorenz D, Koppe U, Gutbier B, Tabeling C, Reppe K, Meixenberger K, Dorhoi A, Ma J, Holmes A, Trendelenburg G, Heimesaat MM, Bereswill S, van der Linden M, Tschopp J, Mitchell TJ, Suttorp N, Opitz B. Witzenrath M, et al. Among authors: opitz b. J Immunol. 2011 Jul 1;187(1):434-40. doi: 10.4049/jimmunol.1003143. Epub 2011 Jun 6. J Immunol. 2011. PMID: 21646297
Streptococcus pneumoniae stimulates a STING- and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs.
Koppe U, Högner K, Doehn JM, Müller HC, Witzenrath M, Gutbier B, Bauer S, Pribyl T, Hammerschmidt S, Lohmeyer J, Suttorp N, Herold S, Opitz B. Koppe U, et al. Among authors: opitz b. J Immunol. 2012 Jan 15;188(2):811-7. doi: 10.4049/jimmunol.1004143. Epub 2011 Dec 12. J Immunol. 2012. PMID: 22156592
Moxifloxacin is not anti-inflammatory in experimental pneumococcal pneumonia.
Müller-Redetzky HC, Wienhold SM, Berg J, Hocke AC, Hippenstiel S, Hellwig K, Gutbier B, Opitz B, Neudecker J, Rückert J, Gruber AD, Kershaw O, Mayer K, Suttorp N, Witzenrath M. Müller-Redetzky HC, et al. Among authors: opitz b. J Antimicrob Chemother. 2015 Mar;70(3):830-40. doi: 10.1093/jac/dku446. Epub 2014 Nov 17. J Antimicrob Chemother. 2015. PMID: 25406299
205 results