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Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung.
Dörner PJ, Anandakumar H, Röwekamp I, Fiocca Vernengo F, Millet Pascual-Leone B, Krzanowski M, Sellmaier J, Brüning U, Fritsche-Guenther R, Pfannkuch L, Kurth F, Milek M, Igbokwe V, Löber U, Gutbier B, Holstein M, Heinz GA, Mashreghi MF, Schulte LN, Klatt AB, Caesar S, Wienhold SM, Offermanns S, Mack M, Witzenrath M, Jordan S, Beule D, Kirwan JA, Forslund SK, Wilck N, Bartolomaeus H, Heimesaat MM, Opitz B. Dörner PJ, et al. Among authors: witzenrath m. Nat Commun. 2024 Mar 30;15(1):2788. doi: 10.1038/s41467-024-47149-z. Nat Commun. 2024. PMID: 38555356 Free PMC article.
Streptococcus pneumoniae induced p38 MAPK- and NF-kappaB-dependent COX-2 expression in human lung epithelium.
N'Guessan PD, Hippenstiel S, Etouem MO, Zahlten J, Beermann W, Lindner D, Opitz B, Witzenrath M, Rosseau S, Suttorp N, Schmeck B. N'Guessan PD, et al. Among authors: witzenrath m. Am J Physiol Lung Cell Mol Physiol. 2006 Jun;290(6):L1131-8. doi: 10.1152/ajplung.00383.2005. Epub 2006 Jan 13. Am J Physiol Lung Cell Mol Physiol. 2006. PMID: 16414978 Free article.
Simvastatin attenuates ventilator-induced lung injury in mice.
Müller HC, Hellwig K, Rosseau S, Tschernig T, Schmiedl A, Gutbier B, Schmeck B, Hippenstiel S, Peters H, Morawietz L, Suttorp N, Witzenrath M. Müller HC, et al. Among authors: witzenrath m. Crit Care. 2010;14(4):R143. doi: 10.1186/cc9209. Epub 2010 Jul 30. Crit Care. 2010. PMID: 20673352 Free PMC article.
Adrenomedullin attenuates ventilator-induced lung injury in mice.
Müller HC, Witzenrath M, Tschernig T, Gutbier B, Hippenstiel S, Santel A, Suttorp N, Rosseau S. Müller HC, et al. Among authors: witzenrath m. Thorax. 2010 Dec;65(12):1077-84. doi: 10.1136/thx.2010.135996. Epub 2010 Oct 22. Thorax. 2010. PMID: 20971983
266 results