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Engineering a human P2X2 receptor with altered ligand selectivity in yeast.
Gardner EC, Tramont C, Bachanová P, Wang C, Do H, Boutz DR, Kar S, Zemelman BV, Gollihar JD, Ellington AD. Gardner EC, et al. Among authors: boutz dr. J Biol Chem. 2024 May;300(5):107248. doi: 10.1016/j.jbc.2024.107248. Epub 2024 Mar 29. J Biol Chem. 2024. PMID: 38556082 Free PMC article.
Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein.
Javanmardi K, Segall-Shapiro TH, Chou CW, Boutz DR, Olsen RJ, Xie X, Xia H, Shi PY, Johnson CD, Annapareddy A, Weaver S, Musser JM, Ellington AD, Finkelstein IJ, Gollihar JD. Javanmardi K, et al. Among authors: boutz dr. Cell Host Microbe. 2022 Sep 14;30(9):1242-1254.e6. doi: 10.1016/j.chom.2022.07.016. Epub 2022 Aug 4. Cell Host Microbe. 2022. PMID: 35988543 Free PMC article.
SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Goike J, Hsieh CL, Horton AP, Gardner EC, Zhou L, Bartzoka F, Wang N, Javanmardi K, Herbert A, Abbassi S, Xie X, Xia H, Shi PY, Renberg R, Segall-Shapiro TH, Terrace CI, Wu W, Shroff R, Byrom M, Ellington AD, Marcotte EM, Musser JM, Kuchipudi SV, Kapur V, Georgiou G, Weaver SC, Dye JM, Boutz DR, McLellan JS, Gollihar JD. Goike J, et al. Among authors: boutz dr. Commun Biol. 2023 Dec 11;6(1):1250. doi: 10.1038/s42003-023-05649-6. Commun Biol. 2023. PMID: 38082099 Free PMC article.
A proteomic survey of widespread protein aggregation in yeast.
O'Connell JD, Tsechansky M, Royal A, Boutz DR, Ellington AD, Marcotte EM. O'Connell JD, et al. Among authors: boutz dr. Mol Biosyst. 2014 Apr;10(4):851-861. doi: 10.1039/c3mb70508k. Epub 2014 Feb 3. Mol Biosyst. 2014. PMID: 24488121 Free PMC article.
Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality.
Goike J, Hsieh CL, Horton A, Gardner EC, Bartzoka F, Wang N, Javanmardi K, Herbert A, Abbassi S, Renberg R, Johanson MJ, Cardona JA, Segall-Shapiro T, Zhou L, Nissly RH, Gontu A, Byrom M, Maranhao AC, Battenhouse AM, Gejji V, Soto-Sierra L, Foster ER, Woodard SL, Nikolov ZL, Lavinder J, Voss WN, Annapareddy A, Ippolito GC, Ellington AD, Marcotte EM, Finkelstein IJ, Hughes RA, Musser JM, Kuchipudi SV, Kapur V, Georgiou G, Dye JM, Boutz DR, McLellan JS, Gollihar JD. Goike J, et al. Among authors: boutz dr. bioRxiv [Preprint]. 2021 Apr 9:2021.04.07.438849. doi: 10.1101/2021.04.07.438849. bioRxiv. 2021. PMID: 33851158 Free PMC article. Preprint.
Rapid characterization of spike variants via mammalian cell surface display.
Javanmardi K, Chou CW, Terrace CI, Annapareddy A, Kaoud TS, Guo Q, Lutgens J, Zorkic H, Horton AP, Gardner EC, Nguyen G, Boutz DR, Goike J, Voss WN, Kuo HC, Dalby KN, Gollihar JD, Finkelstein IJ. Javanmardi K, et al. Among authors: boutz dr. Mol Cell. 2021 Dec 16;81(24):5099-5111.e8. doi: 10.1016/j.molcel.2021.11.024. Mol Cell. 2021. PMID: 34919820 Free PMC article.
Identification and characterization of the constituent human serum antibodies elicited by vaccination.
Lavinder JJ, Wine Y, Giesecke C, Ippolito GC, Horton AP, Lungu OI, Hoi KH, DeKosky BJ, Murrin EM, Wirth MM, Ellington AD, Dörner T, Marcotte EM, Boutz DR, Georgiou G. Lavinder JJ, et al. Among authors: boutz dr. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2259-64. doi: 10.1073/pnas.1317793111. Epub 2014 Jan 27. Proc Natl Acad Sci U S A. 2014. PMID: 24469811 Free PMC article.
44 results