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Extreme Phenotype Sampling and Next Generation Sequencing to Identify Genetic Variants Associated with Tacrolimus in African American Kidney Transplant Recipients.
Mohamed M, Guo B, Wu B, Schladt D, Muthusamy A, Guan W, Abrahante J, Onyeaghala G, Saqr A, Pankratz N, Agarwal G, Mannon R, Matas A, Oetting W, Remmel R, Israni A, Jacobson P, Dorr C. Mohamed M, et al. Among authors: dorr c. Res Sq [Preprint]. 2024 Mar 14:rs.3.rs-4050136. doi: 10.21203/rs.3.rs-4050136/v1. Res Sq. 2024. PMID: 38558983 Free PMC article. Preprint.
Identification of genetic variants associated with tacrolimus metabolism in kidney transplant recipients by extreme phenotype sampling and next generation sequencing.
Dorr CR, Wu B, Remmel RP, Muthusamy A, Schladt DP, Abrahante JE, Guan W, Mannon RB, Matas AJ, Oetting WS, Jacobson PA, Israni AK; for DeKAF Genomics. Dorr CR, et al. Pharmacogenomics J. 2019 Aug;19(4):375-389. doi: 10.1038/s41397-018-0063-z. Epub 2018 Nov 16. Pharmacogenomics J. 2019. PMID: 30442921 Free PMC article.
Tacrolimus trough and dose intra-patient variability and CYP3A5 genotype: Effects on acute rejection and graft failure in European American and African American kidney transplant recipients.
Seibert SR, Schladt DP, Wu B, Guan W, Dorr C, Remmel RP, Matas AJ, Mannon RB, Israni AK, Oetting WS, Jacobson PA. Seibert SR, et al. Among authors: dorr c. Clin Transplant. 2018 Dec;32(12):e13424. doi: 10.1111/ctr.13424. Epub 2018 Oct 31. Clin Transplant. 2018. PMID: 30318646 Free PMC article.
Tacrolimus troughs and genetic determinants of metabolism in kidney transplant recipients: A comparison of four ancestry groups.
Mohamed ME, Schladt DP, Guan W, Wu B, van Setten J, Keating BJ, Iklé D, Remmel RP, Dorr CR, Mannon RB, Matas AJ, Israni AK, Oetting WS, Jacobson PA; DeKAF Genomics and GEN03 Investigators. Mohamed ME, et al. Am J Transplant. 2019 Oct;19(10):2795-2804. doi: 10.1111/ajt.15385. Epub 2019 May 13. Am J Transplant. 2019. PMID: 30953600 Free PMC article.
Pharmacogenomics in kidney transplant recipients and potential for integration into practice.
Nguyen TT, Pearson RA, Mohamed ME, Schladt DP, Berglund D, Rivers Z, Skaar DJ, Wu B, Guan W, van Setten J, Keating BJ, Dorr C, Remmel RP, Matas AJ, Mannon RB, Israni AK, Oetting WS, Jacobson PA. Nguyen TT, et al. Among authors: dorr c. J Clin Pharm Ther. 2020 Dec;45(6):1457-1465. doi: 10.1111/jcpt.13223. Epub 2020 Jul 14. J Clin Pharm Ther. 2020. PMID: 32662547 Free PMC article.
Genomewide Association Study of Tacrolimus Concentrations in African American Kidney Transplant Recipients Identifies Multiple CYP3A5 Alleles.
Oetting WS, Schladt DP, Guan W, Miller MB, Remmel RP, Dorr C, Sanghavi K, Mannon RB, Herrera B, Matas AJ, Salomon DR, Kwok PY, Keating BJ, Israni AK, Jacobson PA; DeKAF Investigators. Oetting WS, et al. Among authors: dorr c. Am J Transplant. 2016 Feb;16(2):574-82. doi: 10.1111/ajt.13495. Epub 2015 Oct 20. Am J Transplant. 2016. PMID: 26485092 Free PMC article.
116 results