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Conditional c-MYC activation in catecholaminergic cells drives distinct neuroendocrine tumors: neuroblastoma vs somatostatinoma.
Wang T, Liu L, Fang J, Jin H, Natarajan S, Sheppard H, Lu M, Turner G, Confer T, Johnson M, Steinberg J, Ha L, Yadak N, Jain R, Picketts DJ, Ma X, Murphy A, Davidoff AM, Glazer ES, Easton J, Chen X, Wang R, Yang J. Wang T, et al. Among authors: confer t. bioRxiv [Preprint]. 2024 Mar 14:2024.03.12.584622. doi: 10.1101/2024.03.12.584622. bioRxiv. 2024. PMID: 38559042 Free PMC article. Preprint.
Targeting the spliceosome through RBM39 degradation results in exceptional responses in high-risk neuroblastoma models.
Singh S, Quarni W, Goralski M, Wan S, Jin H, Van de Velde LA, Fang J, Wu Q, Abu-Zaid A, Wang T, Singh R, Craft D, Fan Y, Confer T, Johnson M, Akers WJ, Wang R, Murray PJ, Thomas PG, Nijhawan D, Davidoff AM, Yang J. Singh S, et al. Among authors: confer t. Sci Adv. 2021 Nov 19;7(47):eabj5405. doi: 10.1126/sciadv.abj5405. Epub 2021 Nov 17. Sci Adv. 2021. PMID: 34788094 Free PMC article.
An integrated single-cell RNA-seq map of human neuroblastoma tumors and preclinical models uncovers divergent mesenchymal-like gene expression programs.
Chapple RH, Liu X, Natarajan S, Alexander MIM, Kim Y, Patel AG, LaFlamme CW, Pan M, Wright WC, Lee HM, Zhang Y, Lu M, Koo SC, Long C, Harper J, Savage C, Johnson MD, Confer T, Akers WJ, Dyer MA, Sheppard H, Easton J, Geeleher P. Chapple RH, et al. Among authors: confer t. bioRxiv [Preprint]. 2024 Apr 22:2023.04.13.536639. doi: 10.1101/2023.04.13.536639. bioRxiv. 2024. PMID: 38712039 Free PMC article. Preprint.
RBM39 degrader invigorates natural killer cells to eradicate neuroblastoma despite cancer cell plasticity.
Singh S, Fang J, Jin H, Van de Velde LA, Wu Q, Cortes A, Morton CL, Woolard MA, Quarni W, Steele JA, Connelly JP, He L, Thorne R, Turner G, Confer T, Johnson M, Caufield WV, Freeman BB, Lockey T, Pruett-Miller SM, Wang R, Davidoff AM, Thomas PG, Yang J. Singh S, et al. Among authors: confer t. bioRxiv [Preprint]. 2024 Mar 25:2024.03.21.586157. doi: 10.1101/2024.03.21.586157. bioRxiv. 2024. PMID: 38585889 Free PMC article. Preprint.
Maternal immunization with distinct influenza vaccine platforms elicits unique antibody profiles that impact the protection of offspring.
Vazquez-Pagan A, Roubidoux EK, Cherry S, Livingston B, Bub T, Lazure L, Sharp B, Confer T, Brigleb PH, Honce R, Whitt KT, Johnson M, Meliopoulos V, Schultz-Cherry S. Vazquez-Pagan A, et al. Among authors: confer t. bioRxiv [Preprint]. 2023 Oct 30:2023.10.30.564827. doi: 10.1101/2023.10.30.564827. bioRxiv. 2023. PMID: 37961247 Free PMC article. Preprint.