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Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis product.
Mishra A, Huang SB, Dubash T, Burr R, Edd JF, Wittner BS, Cunneely QE, Putaturo VR, Deshpande A, Antmen E, Gopinathan KA, Otani K, Miyazawa Y, Kwak JE, Guay SY, Kelly J, Walsh J, Nieman L, Galler I, Chan P, Lawrence MS, Sullivan RJ, Bardia A, Micalizzi DS, Sequist LV, Lee RJ, Franses JW, Ting DT, Brunker PAR, Maheswaran S, Miyamoto DT, Haber DA, Toner M. Mishra A, et al. Among authors: toner m. bioRxiv [Preprint]. 2024 Mar 14:2024.03.13.583573. doi: 10.1101/2024.03.13.583573. bioRxiv. 2024. PMID: 38559183 Free PMC article. Preprint.
A Microfluidic Transistor for Liquid Signal Processing.
Gopinathan KA, Mishra A, Mutlu BR, Edd JF, Toner M. Gopinathan KA, et al. Among authors: toner m. bioRxiv [Preprint]. 2023 Jun 2:2023.05.31.543146. doi: 10.1101/2023.05.31.543146. bioRxiv. 2023. PMID: 37398240 Free PMC article. Preprint.
A microfluidic device for label-free, physical capture of circulating tumor cell clusters.
Sarioglu AF, Aceto N, Kojic N, Donaldson MC, Zeinali M, Hamza B, Engstrom A, Zhu H, Sundaresan TK, Miyamoto DT, Luo X, Bardia A, Wittner BS, Ramaswamy S, Shioda T, Ting DT, Stott SL, Kapur R, Maheswaran S, Haber DA, Toner M. Sarioglu AF, et al. Among authors: toner m. Nat Methods. 2015 Jul;12(7):685-91. doi: 10.1038/nmeth.3404. Epub 2015 May 18. Nat Methods. 2015. PMID: 25984697 Free PMC article.
Microfluidic concentration and separation of circulating tumor cell clusters from large blood volumes.
Edd JF, Mishra A, Dubash TD, Herrera S, Mohammad R, Williams EK, Hong X, Mutlu BR, Walsh JR, Machado de Carvalho F, Aldikacti B, Nieman LT, Stott SL, Kapur R, Maheswaran S, Haber DA, Toner M. Edd JF, et al. Among authors: toner m. Lab Chip. 2020 Feb 7;20(3):558-567. doi: 10.1039/c9lc01122f. Epub 2020 Jan 14. Lab Chip. 2020. PMID: 31934715 Free PMC article.
Ultrahigh-throughput magnetic sorting of large blood volumes for epitope-agnostic isolation of circulating tumor cells.
Mishra A, Dubash TD, Edd JF, Jewett MK, Garre SG, Karabacak NM, Rabe DC, Mutlu BR, Walsh JR, Kapur R, Stott SL, Maheswaran S, Haber DA, Toner M. Mishra A, et al. Among authors: toner m. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):16839-16847. doi: 10.1073/pnas.2006388117. Epub 2020 Jul 8. Proc Natl Acad Sci U S A. 2020. PMID: 32641515 Free PMC article.
Isolation of circulating tumor cells.
Edd JF, Mishra A, Smith KC, Kapur R, Maheswaran S, Haber DA, Toner M. Edd JF, et al. Among authors: toner m. iScience. 2022 Jul 1;25(8):104696. doi: 10.1016/j.isci.2022.104696. eCollection 2022 Aug 19. iScience. 2022. PMID: 35880043 Free PMC article. Review.
Monolithic Chip for High-throughput Blood Cell Depletion to Sort Rare Circulating Tumor Cells.
Fachin F, Spuhler P, Martel-Foley JM, Edd JF, Barber TA, Walsh J, Karabacak M, Pai V, Yu M, Smith K, Hwang H, Yang J, Shah S, Yarmush R, Sequist LV, Stott SL, Maheswaran S, Haber DA, Kapur R, Toner M. Fachin F, et al. Among authors: toner m. Sci Rep. 2017 Sep 7;7(1):10936. doi: 10.1038/s41598-017-11119-x. Sci Rep. 2017. PMID: 28883519 Free PMC article.
557 results