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A systems-biology approach connects aging mechanisms with Alzheimer's disease pathogenesis.
Leventhal MJ, Zanella CA, Kang B, Peng J, Gritsch D, Liao Z, Bukhari H, Wang T, Pao PC, Danquah S, Benetatos J, Nehme R, Farhi S, Tsai LH, Dong X, Scherzer CR, Feany MB, Fraenkel E. Leventhal MJ, et al. Among authors: scherzer cr. bioRxiv [Preprint]. 2024 Mar 17:2024.03.17.585262. doi: 10.1101/2024.03.17.585262. bioRxiv. 2024. PMID: 38559190 Free PMC article. Preprint.
Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies.
Nazeen S, Wang X, Zielinski D, Lam I, Hallacli E, Xu P, Ethier E, Strom R, Zanella CA, Nithianandam V, Ritter D, Henderson A, Saurat N, Afroz J, Nutter-Upham A, Benyamini H, Copty J, Ravishankar S, Morrow A, Mitchel J, Neavin D, Gupta R, Farbehi N, Grundman J, Myers RH, Scherzer CR, Trojanowski JQ, Van Deerlin VM, Cooper AA, Lee EB, Erlich Y, Lindquist S, Peng J, Geschwind DH, Powell J, Studer L, Feany MB, Sunyaev SR, Khurana V. Nazeen S, et al. Among authors: scherzer cr. bioRxiv [Preprint]. 2024 Mar 7:2024.03.03.583145. doi: 10.1101/2024.03.03.583145. bioRxiv. 2024. PMID: 38496508 Free PMC article. Preprint.
Disease progression strikingly differs in research and real-world Parkinson's populations.
Beaulieu-Jones BK, Frau F, Bozzi S, Chandross KJ, Peterschmitt MJ, Cohen C, Coulovrat C, Kumar D, Kruger MJ, Lipnick SL, Fitzsimmons L, Kohane IS, Scherzer CR. Beaulieu-Jones BK, et al. Among authors: scherzer cr. medRxiv [Preprint]. 2024 Feb 18:2024.02.17.24302981. doi: 10.1101/2024.02.17.24302981. medRxiv. 2024. PMID: 38405736 Free PMC article. Updated. Preprint.
Disease progression strikingly differs in research and real-world Parkinson's populations.
Beaulieu-Jones BK, Frau F, Bozzi S, Chandross KJ, Peterschmitt MJ, Cohen C, Coulovrat C, Kumar D, Kruger MJ, Lipnick SL, Fitzsimmons L, Kohane IS, Scherzer CR. Beaulieu-Jones BK, et al. Among authors: scherzer cr. NPJ Parkinsons Dis. 2024 Mar 13;10(1):58. doi: 10.1038/s41531-024-00667-5. NPJ Parkinsons Dis. 2024. PMID: 38480700 Free PMC article.
109 results