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Evidence that conserved essential genes are enriched for pro-longevity factors.
Oz N, Vayndorf EM, Tsuchiya M, McLean S, Turcios-Hernandez L, Pitt JN, Blue BW, Muir M, Kiflezghi MG, Tyshkovskiy A, Mendenhall A, Kaeberlein M, Kaya A. Oz N, et al. Among authors: kaya a. Geroscience. 2022 Aug;44(4):1995-2006. doi: 10.1007/s11357-022-00604-5. Epub 2022 Jun 13. Geroscience. 2022. PMID: 35695982 Free PMC article.
A disease similarity approach identifies short-lived Niemann-Pick type C disease mice with accelerated brain aging as a novel mouse model for Alzheimer's disease and aging research.
Gujjala VA, Klimek I, Abyadeh M, Tyshkovskiy A, Oz N, Castro JP, Gladyshev VN, Newton J, Kaya A. Gujjala VA, et al. Among authors: kaya a. bioRxiv [Preprint]. 2024 May 13:2024.04.19.590328. doi: 10.1101/2024.04.19.590328. bioRxiv. 2024. PMID: 38712089 Free PMC article. Preprint.
Molecular signatures of aneuploidy-driven adaptive evolution.
Kaya A, Mariotti M, Tyshkovskiy A, Zhou X, Hulke ML, Ma S, Gerashchenko MV, Koren A, Gladyshev VN. Kaya A, et al. Nat Commun. 2020 Jan 30;11(1):588. doi: 10.1038/s41467-019-13669-2. Nat Commun. 2020. PMID: 32001709 Free PMC article.
Taurine deficiency as a driver of aging.
Singh P, Gollapalli K, Mangiola S, Schranner D, Yusuf MA, Chamoli M, Shi SL, Lopes Bastos B, Nair T, Riermeier A, Vayndorf EM, Wu JZ, Nilakhe A, Nguyen CQ, Muir M, Kiflezghi MG, Foulger A, Junker A, Devine J, Sharan K, Chinta SJ, Rajput S, Rane A, Baumert P, Schönfelder M, Iavarone F, di Lorenzo G, Kumari S, Gupta A, Sarkar R, Khyriem C, Chawla AS, Sharma A, Sarper N, Chattopadhyay N, Biswal BK, Settembre C, Nagarajan P, Targoff KL, Picard M, Gupta S, Velagapudi V, Papenfuss AT, Kaya A, Ferreira MG, Kennedy BK, Andersen JK, Lithgow GJ, Ali AM, Mukhopadhyay A, Palotie A, Kastenmüller G, Kaeberlein M, Wackerhage H, Pal B, Yadav VK. Singh P, et al. Among authors: kaya a. Science. 2023 Jun 9;380(6649):eabn9257. doi: 10.1126/science.abn9257. Epub 2023 Jun 9. Science. 2023. PMID: 37289866 Free PMC article.
1,351 results