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Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells.
Brennan PJ, Saunders RE, Spanou M, Serafini M, Sun L, Heger GP, Konopacka A, Beveridge RD, Gordon L, Bunally SB, Saudemont A, Benowitz AB, Martinez-Fleites C, Queisser MA, An H, Deane CM, Hann MM, Brayshaw LL, Conway SJ. Brennan PJ, et al. bioRxiv [Preprint]. 2024 Mar 16:2024.03.15.585309. doi: 10.1101/2024.03.15.585309. bioRxiv. 2024. PMID: 38559242 Free PMC article. Preprint.
Structure and dynamics determine G protein coupling specificity at a class A GPCR.
Casiraghi M, Wang H, Brennan P, Habrian C, Hubner H, Schmidt MF, Maul L, Pani B, Bahriz SM, Xu B, White E, Sunahara RK, Xiang YK, Lefkowitz RJ, Isacoff EY, Nucci N, Gmeiner P, Lerch M, Kobilka BK. Casiraghi M, et al. bioRxiv [Preprint]. 2024 Apr 12:2024.03.28.587240. doi: 10.1101/2024.03.28.587240. bioRxiv. 2024. PMID: 38586060 Free PMC article. Preprint.
TCF1-LEF1 co-expression identifies a multipotent progenitor cell (TH2-MPP) across human allergic diseases.
Kratchmarov R, Djeddi S, Dunlap G, He W, Jia X, Burk CM, Ryan T, McGill A, Allegretti JR, Kataru RP, Mehrara BJ, Taylor EM, Agarwal S, Bhattacharyya N, Bergmark RW, Maxfield AZ, Lee S, Roditi R, Dwyer DF, Boyce JA, Buchheit KM, Laidlaw TM, Shreffler WG, Rao DA, Gutierrez-Arcelus M, Brennan PJ. Kratchmarov R, et al. Among authors: brennan pj. Nat Immunol. 2024 May;25(5):902-915. doi: 10.1038/s41590-024-01803-2. Epub 2024 Apr 8. Nat Immunol. 2024. PMID: 38589618
Providing Remote Aid During a Humanitarian Crisis.
Kaplan LJ, Levin S, Yelon J, Cannon JM, Mehta S, Reilly PM, Kovach SJ 3rd, Donegan DJ, Claycomb K, Savchenko-Fullerton M, Filonenko E, Maiko V, Kuzmov R, Radega Y, Pashinskiy V, Demyan YY, Plesha P, Demyan Y, Vinnytskiy D, Gaulton GN, Brennan PJ. Kaplan LJ, et al. Among authors: brennan pj. Crit Care Explor. 2023 Oct 27;5(11):e0992. doi: 10.1097/CCE.0000000000000992. eCollection 2023 Nov. Crit Care Explor. 2023. PMID: 38304707 Free PMC article.
PPARγ agonist treatment reduces fibroadipose tissue in secondary lymphedema by exhausting fibroadipogenic PDGFRα+ mesenchymal cells.
Chen Z, Ghavimi SAA, Wu M, McNamara J, Barreiro O, Maridas D, Kratchmarov R, Siegel A, Djeddi S, Gutierrez-Arcelus M, Brennan PJ, Padera TP, von Andrian U, Mehrara B, Greene AK, Kahn CR, Orgill DP, Sinha I, Rosen V, Agarwal S. Chen Z, et al. Among authors: brennan pj. JCI Insight. 2023 Dec 22;8(24):e165324. doi: 10.1172/jci.insight.165324. JCI Insight. 2023. PMID: 38131378 Free PMC article.
Early-life fecal metabolomics of food allergy.
Lee-Sarwar KA, Chen YC, Lasky-Su J, Kelly RS, Zeiger RS, O'Connor GT, Bacharier LB, Jia X, Beigelman A, Gold DR, Laranjo N, Bunyavanich S, Weiss ST, Litonjua AA, Brennan PJ. Lee-Sarwar KA, et al. Among authors: brennan pj. Allergy. 2023 Feb;78(2):512-521. doi: 10.1111/all.15602. Epub 2022 Dec 7. Allergy. 2023. PMID: 36448508 Free PMC article.
569 results