Martinez-Fleites C - Search Results

1

Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells.

Brennan PJ, Saunders RE, Spanou M, Serafini M, Sun L, Heger GP, Konopacka A, Beveridge RD, Gordon L, Bunally SB, Saudemont A, Benowitz AB, Martinez-Fleites C, Queisser MA, An H, Deane CM, Hann MM, Brayshaw LL, Conway SJ. Brennan PJ, et al. Among authors: martinez fleites c. bioRxiv [Preprint]. 2024 Mar 16:2024.03.15.585309. doi: 10.1101/2024.03.15.585309. bioRxiv. 2024. PMID: 38559242 Free PMC article. Preprint.

2

The role of small molecules in cell and gene therapy.

Brayshaw LL, Martinez-Fleites C, Athanasopoulos T, Southgate T, Jespers L, Herring C. Brayshaw LL, et al. Among authors: martinez fleites c. RSC Med Chem. 2020 Dec 24;12(3):330-352. doi: 10.1039/d0md00221f. eCollection 2021 Mar 1. RSC Med Chem. 2020. PMID: 34046619 Free PMC article. Review.

3

Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF.

McMillan D, Martinez-Fleites C, Porter J, Fox D 3rd, Davis R, Mori P, Ceska T, Carrington B, Lawson A, Bourne T, O'Connell J. McMillan D, et al. Among authors: martinez fleites c. Nat Commun. 2021 Jan 25;12(1):582. doi: 10.1038/s41467-020-20828-3. Nat Commun. 2021. PMID: 33495441 Free PMC article.

4

Building custom polysaccharides in vitro with an efficient, broad-specificity xyloglucan glycosynthase and a fucosyltransferase.

Spadiut O, Ibatullin FM, Peart J, Gullfot F, Martinez-Fleites C, Ruda M, Xu C, Sundqvist G, Davies GJ, Brumer H. Spadiut O, et al. Among authors: martinez fleites c. J Am Chem Soc. 2011 Jul 20;133(28):10892-900. doi: 10.1021/ja202788q. Epub 2011 Jun 27. J Am Chem Soc. 2011. PMID: 21618981 Free PMC article.

5

Substrate and metal ion promiscuity in mannosylglycerate synthase.

Nielsen MM, Suits MD, Yang M, Barry CS, Martinez-Fleites C, Tailford LE, Flint JE, Dumon C, Davis BG, Gilbert HJ, Davies GJ. Nielsen MM, et al. Among authors: martinez fleites c. J Biol Chem. 2011 Apr 29;286(17):15155-64. doi: 10.1074/jbc.M110.199844. Epub 2011 Feb 2. J Biol Chem. 2011. PMID: 21288903 Free PMC article.

6

GlaxoSmithKline Award Lecture. The O-GlcNAc modification: three-dimensional structure, enzymology and the development of selective inhibitors to probe disease.

Davies GJ, Martinez-Fleites C. Davies GJ, et al. Among authors: martinez fleites c. Biochem Soc Trans. 2010 Oct;38(5):1179-88. doi: 10.1042/BST0381179. Biochem Soc Trans. 2010. PMID: 20863281 Review.

7

Mechanistic insight into enzymatic glycosyl transfer with retention of configuration through analysis of glycomimetic inhibitors.

Errey JC, Lee SS, Gibson RP, Martinez Fleites C, Barry CS, Jung PM, O'Sullivan AC, Davis BG, Davies GJ. Errey JC, et al. Among authors: martinez fleites c. Angew Chem Int Ed Engl. 2010 Feb 8;49(7):1234-7. doi: 10.1002/anie.200905096. Angew Chem Int Ed Engl. 2010. PMID: 20077550 No abstract available.

8

Structures of two truncated phage-tail hyaluronate lyases from Streptococcus pyogenes serotype M1.

Martinez-Fleites C, Smith NL, Turkenburg JP, Black GW, Taylor EJ. Martinez-Fleites C, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Oct 1;65(Pt 10):963-6. doi: 10.1107/S1744309109032813. Epub 2009 Sep 18. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 19850999 Free PMC article.

9

Structural analyses of enzymes involved in the O-GlcNAc modification.

Martinez-Fleites C, He Y, Davies GJ. Martinez-Fleites C, et al. Biochim Biophys Acta. 2010 Feb;1800(2):122-33. doi: 10.1016/j.bbagen.2009.07.019. Epub 2009 Jul 30. Biochim Biophys Acta. 2010. PMID: 19647042 Review.

10

The crystal structure of a family GH25 lysozyme from Bacillus anthracis implies a neighboring-group catalytic mechanism with retention of anomeric configuration.

Martinez-Fleites C, Korczynska JE, Davies GJ, Cope MJ, Turkenburg JP, Taylor EJ. Martinez-Fleites C, et al. Carbohydr Res. 2009 Sep 8;344(13):1753-7. doi: 10.1016/j.carres.2009.06.001. Epub 2009 Jun 6. Carbohydr Res. 2009. PMID: 19595298

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