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Route of 41BB/41BBL Costimulation Determines Effector Function of B7-H3-CAR.CD28ζ T Cells.
Nguyen P, Okeke E, Clay M, Haydar D, Justice J, O'Reilly C, Pruett-Miller S, Papizan J, Moore J, Zhou S, Throm R, Krenciute G, Gottschalk S, DeRenzo C. Nguyen P, et al. Among authors: derenzo c. Mol Ther Oncolytics. 2020 Jun 23;18:202-214. doi: 10.1016/j.omto.2020.06.018. eCollection 2020 Sep 25. Mol Ther Oncolytics. 2020. PMID: 32728609 Free PMC article.
CD47 expression is critical for CAR T-cell survival in vivo.
Beckett AN, Chockley P, Pruett-Miller SM, Nguyen P, Vogel P, Sheppard H, Krenciute G, Gottschalk S, DeRenzo C. Beckett AN, et al. Among authors: derenzo c. J Immunother Cancer. 2023 Mar;11(3):e005857. doi: 10.1136/jitc-2022-005857. J Immunother Cancer. 2023. PMID: 36918226 Free PMC article.
CAR T-cell Design-dependent Remodeling of the Brain Tumor Immune Microenvironment Modulates Tumor-associated Macrophages and Anti-glioma Activity.
Haydar D, Ibañez-Vega J, Crawford JC, Chou CH, Guy CS, Meehl M, Yi Z, Perry S, Laxton J, Cunningham T, Langfitt D, Vogel P, DeRenzo C, Gottschalk S, Roussel MF, Thomas PG, Krenciute G. Haydar D, et al. Among authors: derenzo c. Cancer Res Commun. 2023 Dec 1;3(12):2430-2446. doi: 10.1158/2767-9764.CRC-23-0424. Cancer Res Commun. 2023. PMID: 37971169 Free PMC article.
CAR T Cell Therapy for Solid Tumors: Bright Future or Dark Reality?
Wagner J, Wickman E, DeRenzo C, Gottschalk S. Wagner J, et al. Among authors: derenzo c. Mol Ther. 2020 Nov 4;28(11):2320-2339. doi: 10.1016/j.ymthe.2020.09.015. Epub 2020 Sep 16. Mol Ther. 2020. PMID: 32979309 Free PMC article. Review.
Cell-surface antigen profiling of pediatric brain tumors: B7-H3 is consistently expressed and can be targeted via local or systemic CAR T-cell delivery.
Haydar D, Houke H, Chiang J, Yi Z, Odé Z, Caldwell K, Zhu X, Mercer KS, Stripay JL, Shaw TI, Vogel P, DeRenzo C, Baker SJ, Roussel MF, Gottschalk S, Krenciute G. Haydar D, et al. Among authors: derenzo c. Neuro Oncol. 2021 Jun 1;23(6):999-1011. doi: 10.1093/neuonc/noaa278. Neuro Oncol. 2021. PMID: 33320196 Free PMC article.
30 results